Diabetic Eye Disease



Pilot Assessment of EyeArt as an Automated Diabetic Retinopathy Screening Tool


Condition:   Diabetic Retinopathy
Interventions:   Procedure: Color fundus photography;   Drug: Mydriatic Agent
Sponsors:   Eyenuk, Inc.;   National Eye Institute (NEI)
Enrolling by invitation - verified March 2017


The Efficacy of Intravitreal Aflibercept Injection in Improvement of Retinal Nonperfusion in Diabetic Retinopathy


Condition:   Diabetic Retinopathy
Intervention:   Drug: Intravitreal Aflibercept injection
Sponsor:   Asan Medical Center
Recruiting - verified December 2016


A Multi-center Study to Evaluate Performance of an Automated Device for the Detection of Diabetic Retinopathy


Condition:   Diabetic Retinopathy
Intervention:  
Sponsors:   IDx LLC;   The EMMES Corporation
Enrolling by invitation - verified December 2016


Automated Diagnostic Test for Diabetic Retinopathy in Brazilian Mass Screening


Condition:   Diabetic Retinopathy
Intervention:   Other: Diabetic Retinopathy screening
Sponsor:   Retina Clinic, Sao Paulo, Brazil
Completed - verified October 2016


Progression of Diabetic Retinopathy. Identification of Signs and Surrogate Outcomes


Condition:   Diabetic Retinopathy
Intervention:  
Sponsor:   Association for Innovation and Biomedical Research on Light and Image
Recruiting - verified January 2017


Conbercept vs Panretinal Photocoagulation for the Management of Proliferative Diabetic Retinopathy


Condition:   Proliferative Diabetic Retinopathy
Interventions:   Drug: intravitreal injection of conbercept;   Device: PRP
Sponsor:   Sun Yat-sen University
Active, not recruiting - verified September 2016


Genetic Markers and Proliferative Diabetic Retinopathy


Condition:   Proliferative Diabetic Retinopathy
Intervention:   Genetic: genetic analysis
Sponsor:   CHU de Reims
Recruiting - verified August 2016


Intravitreal Aflibercept for Retinal Non-Perfusion in Proliferative Diabetic Retinopathy


Condition:   Proliferative Diabetic Retinopathy
Intervention:   Drug: Aflibercept
Sponsors:   Charles C Wykoff, PhD, MD;   Regeneron Pharmaceuticals
Recruiting - verified February 2017


Diabetic Retinopathy Screening in Private Practice


Condition:   Diabetic Retinopathy
Interventions:   Other: Free screening group;   Other: Pay screening group ($150);   Other: Pay screening group ($300)
Sponsor:   The University of Hong Kong
Not yet recruiting - verified August 2016


Intravitreal Injection of Ranibizumab Versus Sham Before Vitrectomy in Patients With Proliferative Diabetic Retinopathy


Condition:   Proliferative Diabetic Retinopathy
Interventions:   Drug: ranibizumab;   Drug: sham;   Procedure: pars plana vitrectomy
Sponsor:   Sun Yat-sen University
Recruiting - verified August 2016


Study to Evaluate Effects of Emixustat Hydrochloride in Subjects With Proliferative Diabetic Retinopathy


Condition:   Proliferative Diabetic Retinopathy
Interventions:   Drug: emixustat hydrochloride;   Other: Placebo
Sponsor:   Acucela Inc.
Recruiting - verified March 2017


Study of the Efficacy and Safety of Intravitreal (IVT) Aflibercept for the Improvement of Moderately Severe to Severe Nonproliferative Diabetic Retinopathy (NPDR)


Condition:   Nonproliferative Diabetic Retinopathy
Interventions:   Drug: Intravitreal aflibercept injection [IAI];   Drug: Sham
Sponsor:   Regeneron Pharmaceuticals
Recruiting - verified May 2017


Phase III Study of Compound Danshen Dripping Pills to Treat Diabetic Retinopathy


Condition:   Non-proliferative Diabetic Retinopathy
Interventions:   Drug: Compound danshen dripping pills;   Drug: Placebo
Sponsor:   Tasly Pharmaceuticals, Inc.
Active, not recruiting - verified March 2017


Evaluation of Progression of Diabetic Retinopathy With Rapid Correction of Hyperglycemia


Condition:   Diabetic Retinopathy
Intervention:   Other: Initiation of treatment of diabetes
Sponsor:   Temple University
Recruiting - verified May 2017


25-Gauge Vitrectomy With Ranibizumab or Triamcinolone Acetonide on Proliferative Diabetic Retinopathy in China


Condition:   Proliferative Diabetic Retinopathy
Interventions:   Drug: Ranibizumab;   Drug: Triamcinolone Acetonide
Sponsors:   JUNYAN ZHANG;   The First People's Hospital of Xuzhou
Recruiting - verified August 2016


The Individually Marked Panretinal lasEr phoTokoagUlation for Proliferative Diabetic Retinopathy Study - DETECT


Condition:   Proliferative Diabetic Retinopathy
Intervention:   Procedure: Panretinal laser photocoagulation
Sponsors:   Odense University Hospital;   University of Southern Denmark;   Moorfields Eye Hospital NHS Foundation Trust;   National University, Singapore;   Yamagata University
Active, not recruiting - verified June 2016


Collaborative Care for Depression and Diabetic Retinopathy in African Americans


Condition:   Diabetic Retinopathy
Intervention:   Behavioral: Behavioral Activation
Sponsors:   Thomas Jefferson University;   Wills Eye
Active, not recruiting - verified October 2016


Analysis of Angiogenic Factor Levels in Eyes With Diabetic Retinopathy


Condition:   Diabetic Retinopathy
Intervention:  
Sponsor:   Kyungpook National University
Recruiting - verified August 2016


Prevention of Macular Edema In Patients With Diabetic Retinopathy Undergoing Cataract Surgery


Condition:   Diabetic Retinopathy
Interventions:   Drug: Aflibercept;   Drug: Sham
Sponsors:   Rishi Singh;   Regeneron Pharmaceuticals
Recruiting - verified April 2017


RETeval Study for Diabetic Retinopathy


Condition:   Diabetic Retinopathy
Intervention:   Device: RETeval
Sponsors:   Inoveon Corporation;   LKC Technologies, Inc.;   National Eye Institute (NEI)
Completed - verified March 2017


Treatment With Intravitreal Aflibercept Injection For Proliferative Diabetic Retinopathy, The A.C.T Study


Condition:   Proliferative Diabetic Retinopathy
Intervention:   Drug: Intravitreal Aflibercept Injection (IAI)
Sponsors:   Ophthalmic Consultants of Long Island;   Regeneron Pharmaceuticals
Completed - verified June 2016


Propranolol for Diabetic Retinopathy


Condition:   Proliferative Diabetic Retinopathy
Intervention:   Drug: Propranolol
Sponsor:   University of Wisconsin, Madison
Completed - verified March 2017


Prompt Panretinal Photocoagulation Versus Ranibizumab+Deferred Panretinal Photocoagulation for Proliferative Diabetic Retinopathy


Condition:   Proliferative Diabetic Retinopathy
Interventions:   Other: Prompt Panretinal Photocoagulation;   Drug: 0.5-mg Ranibizumab;   Other: Deferred panretinal photocoagulation
Sponsors:   Jaeb Center for Health Research;   National Eye Institute (NEI);   Genentech, Inc.
Active, not recruiting - verified December 2016


Protein Kinase C (PKC) Inhibitor-Diabetic Retinopathy Phase 3 Study


Condition:   Diabetic Retinopathy
Interventions:   Drug: ruboxistaurin;   Drug: placebo
Sponsor:   Chromaderm, Inc.
Completed - verified August 2016


Blood Factors and Diabetic Retinopathy


Condition:   Diabetic Retinopathy
Intervention:  
Sponsor:   National Eye Institute (NEI)
Completed - verified December 7, 2010

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