Blindness



Vitamin A Liver Reserves and Serum Markers of Vitamin A in US Adults at Time of Death


Conditions:   Vitamin A Deficiency;   Vitamin A Toxicity
Intervention:  
Sponsors:   University of Wisconsin, Madison;   National Institute on Deafness and Other Communication Disorders (NIDCD)
Completed


The Effects of Biscuits Containing Red Palm Oil on School Children With Vitamin A Deficiency in West and East Malaysia


Condition:   Vitamin A Deficiency in Children
Interventions:   Dietary Supplement: red palm shortening group;   Dietary Supplement: palm shortening group
Sponsors:   Malaysia Palm Oil Board;   University of Malaya
Recruiting


Multisensory Body and Space Representations (BASES-EXTINCTION)


Conditions:   Healthy;   Blindness
Interventions:   Other: Electrooculogram (EOG);   Other: Surface Electromyography (EMG);   Other: Electrodermal response;   Other: Changes in skin temperature;   Other: MRI;   Other: MEG;   Other: Transcranial magnetic stimulation (TMS);   Other: Transcranial electrical stimulation in direct current (tDCS)
Sponsor:   Hospices Civils de Lyon
Recruiting


Effects of Transcranial Direct Current Stimulation With Proprioceptive Training in Blind People


Conditions:   Blindness, Acquired;   Blindness Congenital
Interventions:   Device: active tDCS;   Device: sham tDCS;   Other: Dynamic proprioceptive exercises;   Other: static proprioceptive exercises
Sponsors:   Salgado Institute of Integral Health;   University of Nove de Julho
Not yet recruiting


Low-vision Rehabilitation Program for Low-vision Patients and Care Givers


Conditions:   Low Vision, One Eye, Unspecified Eye;   Low Vision Blindness;   Low Vision Aids
Interventions:   Other: Low-vision rehabilitation program;   Other: No Intervention
Sponsor:   Lawson Health Research Institute
Not yet recruiting


Laminar Drainage Implant: Safety of a Novel Surgical Treatment for Refractory Glaucoma.


Conditions:   Glaucoma;   Blindness, Acquired;   End-Stage Glaucoma;   Glaucoma Traumatic
Intervention:   Device: Laminar drainage implant surgery.
Sponsor:   Federal University of Minas Gerais
Completed


A Clinical Study to Evaluate the KeraKlear Keratoprosthesis in Patients With Corneal Opacity


Condition:   Corneal Blindness
Intervention:   Device: KeraKlear Non-Penetrating Keratoprosthesis
Sponsors:   KeraMed, Inc.;   National Eye Institute (NEI);   ClinReg Consulting Services, Inc.
Recruiting


Study to Evaluate QR-110 in Subjects With Leber's Congenital Amaurosis (LCA) Due to the c.2991+1655A>G Mutation (p.Cys998X) in the CEP290 Gene


Condition:   Leber's Congenital Amaurosis
Intervention:   Drug: QR-110
Sponsor:   ProQR Therapeutics
Recruiting


Visual Information Restoration and Rehabilitation Via Sensory Substitution Technology in Children


Condition:   Blindness
Intervention:   Device: BrainPort V200 Device
Sponsor:   University of Pittsburgh
Recruiting


Development of a Cortical Visual Neuroprosthesis for the Blind


Condition:   Blindness
Intervention:   Procedure: Minicraniotomy
Sponsors:   Universidad Miguel Hernandez de Elche;   Hospital IMED Elche
Recruiting


Evaluation of a Night Spectacle Correction Concerning an Improvement of Mesopic Vision Quality


Condition:   Myopia-Night Blindness
Intervention:   Device: Spectacle/Glasses
Sponsors:   University of Applied Sciences Jena;   IGA OPTIC EG
Completed


Genetic Decryption of Leber Congenital Amaurosis (LCA) in a Large Cohort of Independent Families.


Condition:   Leber Congenital Amaurosis
Intervention:  
Sponsor:   Assistance Publique - Hôpitaux de Paris
Completed


Stem Cells Therapy for Corneal Blindness


Conditions:   Corneal Injuries;   Corneal Burns;   Corneal Scars and Opacities
Intervention:   Biological: Ex-vivo cultivated limbal stem cell pool
Sponsor:   L.V. Prasad Eye Institute
Recruiting


Efficacy of Biofortified Maize to Improve Maternal and Infant Vitamin A Status


Condition:   Vitamin A Deficiency
Interventions:   Dietary Supplement: Conventional white maize;   Dietary Supplement: Provitamin A carotenoid biofortified maize;   Dietary Supplement: Preformed vitamin A fortified maize
Sponsors:   Johns Hopkins Bloomberg School of Public Health;   University of California, Davis;   Newcastle University;   HarvestPlus
Completed


Clinical Trial of Gene Therapy for the Treatment of Leber Congenital Amaurosis (LCA)


Condition:   Leber Congenital Amaurosis
Intervention:   Biological: AAV RPE65
Sponsor:   MeiraGTx UK II Ltd
Recruiting


Effects of EED on Zn Absorption and Retention in Children From a Standard Dose


Conditions:   Environmental Enteric Dysfunction;   Zinc Deficiency;   Vitamin A Deficiency
Interventions:   Drug: 3 mg zinc sulfate supplement;   Drug: 0.5 mg of 13C10-retinyl-acetate
Sponsors:   University of Colorado, Denver;   International Centre for Diarrhoeal Disease Research, Bangladesh
Recruiting


Natural History Study of Patients With Leber Congenital Amaurosis Associated With Mutations in RPE65


Condition:   Leber Congenital Amaurosis
Intervention:  
Sponsor:   MeiraGTx UK II Ltd
Recruiting


Compensation for Blindness With the Intelligent Retinal Implant System (IRIS V2) in Patients With Retinal Dystrophy


Conditions:   Retinitis Pigmentosa;   Cone Rod Dystrophy;   Choroideremia
Intervention:   Device: Intelligent Retinal Implant System
Sponsor:   Pixium Vision SA
Active, not recruiting


The Efficacy of Pro-vitamin A Biofortified Cassava on Vitamin A Status in Nigerian Preschool Children


Condition:   Vitamin A Deficiency
Interventions:   Other: Pro-vitamin A biofortified cassava;   Other: White cassava
Sponsors:   Wageningen University;   University of Ibadan;   International Institute for Tropical Agriculture
Completed


Inherited Retinal Degenerative Disease Registry


Conditions:   Eye Diseases Hereditary;   Retinal Disease;   Achromatopsia;   Bardet-Biedl Syndrome;   Bassen-Kornzweig Syndrome;   Batten Disease;   Best Disease;   Choroidal Dystrophy;   Choroideremia;   Cone Dystrophy;   Cone-Rod Dystrophy;   Congenital Stationary Night Blindness;   Enhanced S-Cone Syndrome;   Fundus Albipunctatus;   Goldmann-Favre Syndrome;   Gyrate Atrophy;   Juvenile Macular Degeneration;   Kearns-Sayre Syndrome;   Leber Congenital Amaurosis;   Refsum Syndrome;   Retinitis Pigmentosa;   Retinitis Punctata Albescens;   Retinoschisis;   Rod-Cone Dystrophy;   Rod Dystrophy;   Rod Monochromacy;   Stargardt Disease;   Usher Syndrome
Intervention:  
Sponsor:   Foundation Fighting Blindness Clinical Research Institute
Recruiting


Evaluating Color Perception Under LED Red/Green and Green Dominant Light


Condition:   Color Blindness, Acquired
Interventions:   Device: White LED Flashlight;   Device: Red/Green Green Dominant LED Flashlight
Sponsor:   University of Colorado, Denver
Recruiting


Phase 1 Follow-on Study of AAV2-hRPE65v2 Vector in Subjects With Leber Congenital Amaurosis (LCA) 2


Condition:   Leber Congenital Amaurosis
Intervention:   Biological: AAV2-hRPE65v2
Sponsor:   Spark Therapeutics
Active, not recruiting


Melatonin Studies of Totally Blind Children


Conditions:   Sleep Disorder;   Blindness
Intervention:   Drug: Melatonin
Sponsor:   Oregon Health and Science University
Unknown status


Phase 1/2 Safety and Efficacy Study of AAV-RPE65 Vector to Treat Leber Congenital Amaurosis


Condition:   Leber Congenital Amaurosis
Intervention:   Biological: rAAV2-CB-hRPE65
Sponsors:   Applied Genetic Technologies Corp;   Oregon Health and Science University;   University of Massachusetts, Worcester
Active, not recruiting


Safety Study in Subjects With Leber Congenital Amaurosis


Condition:   Leber Congenital Amaurosis
Intervention:   Biological: AAV2-hRPE65v2
Sponsor:   Spark Therapeutics
Active, not recruiting

Refine Your Search Advanced Search