Diabetes (Type 1)



Group Education Curriculum for Older Teens With Type 1 Diabetes


Condition:   Type 1 Diabetes Mellitus
Intervention:   Behavioral: Intervention
Sponsor:   Boston Children’s Hospital
Not yet recruiting - verified May 2017


Vitamin D and Residual Beta-Cell Function in Type 1 Diabetes


Condition:   Type 1 Diabetes
Interventions:   Drug: Ergocalciferol;   Other: Placebo
Sponsor:   University of Massachusetts, Worcester
Not yet recruiting - verified April 2017


Use of Continuous Glucose Monitoring System With Intensive Feedback in Adolescents With Poorly Controlled Type 1 Diabetes


Condition:   Type 1 Diabetes
Interventions:   Device: CGMS Device;   Other: No Device
Sponsor:   New York University School of Medicine
Enrolling by invitation - verified January 2017


Sleep, Coping and Executive Functioning in Youth With Type 1 Diabetes


Condition:   Diabetes Mellitus, Type 1
Intervention:   Other: No intervention
Sponsor:   Yale University
Enrolling by invitation - verified September 2016


Study the Feasibility of Permanent Use of inControl for the Treatment of Type 1 Diabetes


Condition:   Type 1 Diabetes
Intervention:   Device: insulin pump to inControl AP platform
Sponsors:   University Hospital, Montpellier;   MEDBIOMED, Montpellier, France;   Jaeb Center for Health Research;   University of Virginia
Recruiting - verified November 2016


A Phase 2, Multicentre, Randomized, Double-blind, Placebo-controlled Study in Patients With New-onset Type 1 Diabetes


Condition:   Diabetes Mellitus, Insulin-Dependent
Interventions:   Drug: Ladarixin;   Drug: Placebo
Sponsor:   Dompé Farmaceutici S.p.A
Recruiting - verified September 2016


Gene-virus Interactions Implicated in Type 1 Diabetes


Condition:   Type 1 Diabetes
Intervention:   Genetic: Enterovirus vaccination
Sponsor:   Hospices Civils de Lyon
Not yet recruiting - verified June 2016


Insulin Requirement for Pure-protein Meal in Children With Type 1 Diabetes on Insulin Pumps.


Condition:   Diabetes type1
Interventions:   Drug: Insulin glulisine;   Drug: Insulin aspart;   Drug: Insulin lispro
Sponsor:   Medical University of Warsaw
Recruiting - verified January 2016


Modulation of STAT3 Signaling With Siltuximab in Type 1 Diabetes


Condition:   Type 1 Diabetes
Intervention:   Drug: Siltuximab
Sponsors:   Carla Greembaum, MD;   Janssen Research & Development, LLC
Active, not recruiting - verified March 2017


Young With Diabetes Type 1 - Test of an mHealth App


Condition:   Diabetes Mellitus, Type 1
Intervention:   Device: Young with Diabetes - app
Sponsors:   Nordsjaellands Hospital;   Herlev Hospital;   Steno Diabetes Center;   Zealand University Hospital
Completed - verified December 2015


Incretin-based Therapy in Preclinical Type 1 Diabetes in Adults


Condition:   Type 1 Diabetes
Interventions:   Drug: Victoza®;   Drug: Placebo
Sponsors:   University of Oulu;   Oulu University Hospital;   Tampere University Hospital;   Turku University Hospital
Enrolling by invitation - verified September 2016


The Safety and Efficacy of Dapagliflozin Therapy in Combination With Insulin in Japanese Subjects With Type 1 Diabetes Mellitus (T1DM)


Condition:   Type 1 Diabetes Mellitus
Interventions:   Drug: Dapagliflozin 5 mg;   Drug: Dapagliflozin 10mg
Sponsor:   AstraZeneca
Active, not recruiting - verified April 2017


Effect of a Fixed Pramlintide: Insulin Dose Ratio on Postprandial Glucose in Type 1 Diabetes Mellitus


Condition:   Type 1 Diabetes Mellitus
Interventions:   Drug: Pramlintide acetate;   Drug: Placebo;   Drug: Lispro insulin U-100;   Drug: Regular insulin U-100
Sponsors:   AstraZeneca;   Juvenile Diabetes Research Foundation
Completed - verified September 2016


Albiglutide Versus Placebo in Insulin-treated Subjects With New-onset Type 1 Diabetes Mellitus


Condition:   Diabetes Mellitus, Type 1
Interventions:   Biological: Albiglutide weekly injection;   Biological: Placebo weekly injection;   Biological: Insulin
Sponsor:   GlaxoSmithKline
Active, not recruiting - verified May 2017


Pancreas Volume in Preclinical Type 1 Diabetes


Condition:   Type 1 Diabetes
Intervention:   Procedure: MRI, US, and blood samples
Sponsor:   University of Florida
Recruiting - verified April 2017


ATG-GCSF in New Onset Type 1 Diabetes


Condition:   Diabetes Mellitus, Type 1
Interventions:   Drug: Anti-Thymocyte Globulin (ATG);   Drug: Granulocyte colony stimulating factor (GCSF);   Drug: Placebo (for ATG);   Drug: Placebo (for GCSF)
Sponsors:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   National Institute of Allergy and Infectious Diseases (NIAID);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   National Center for Research Resources (NCRR);   Juvenile Diabetes Research Foundation;   American Diabetes Association;   Sanofi;   The Leona M. and Harry B. Helmsley Charitable Trust;   Amgen
Active, not recruiting - verified July 2016


Telemedicine for Adolescents With Insulin-dependent Diabetes


Condition:   Type 1 Diabetes
Interventions:   Other: Telemedicine;   Other: Control
Sponsor:   Texas Tech University Health Sciences Center
Active, not recruiting - verified April 2017


Clinical Trial of Efficiency and Safety of Subetta in the Combined Treatment of Patients With Type I Diabetes Mellitus


Condition:   Type I Diabetes Mellitus
Interventions:   Drug: Subetta;   Drug: Placebo
Sponsor:   Materia Medica Holding
Completed - verified December 2016


Islet Allotransplantation in Type 1 Diabetes


Condition:   Type 1 Diabetes
Intervention:   Drug: Human Pancreatic Islets
Sponsor:   Ohio State University
Enrolling by invitation - verified February 2017


Imaging of Type 1 Diabetes Progression


Condition:   Type 1 Diabetes
Intervention:   Drug: ferumoxytol
Sponsors:   Jason Gaglia;   National Institute of Allergy and Infectious Diseases (NIAID);   Harvard Medical School
Active, not recruiting - verified April 2017


Diabetes Care Management Compared to Standard Diabetes Care in Adolescents and Young Adults With Type 1 Diabetes


Condition:   Type 1 Diabetes
Intervention:   Other: Transition Coordinator
Sponsors:   University of Western Ontario, Canada;   Juvenile Diabetes Research Foundation
Active, not recruiting - verified December 2016


Comparison Between GLP 1 Analogues and DPP 4 Inhibitors in Type 1 Diabetes Mellitus


Condition:   Type 1 Diabetes
Interventions:   Drug: Insulin;   Drug: Sitagliptin;   Drug: Exenatide
Sponsor:   Command Hospital, India
Completed - verified July 2016


Effect of Metabolic Control at Onset of Diabetes on Progression of Type 1 Diabetes


Condition:   Type 1 Diabetes
Interventions:   Device: Closed loop;   Device: Home glucose monitoring;   Device: Insulin pump;   Device: Continuous glucose monitor
Sponsor:   Jaeb Center for Health Research
Terminated - verified November 2016


Trial of Intranasal Insulin in Children and Young Adults at Risk of Type 1 Diabetes


Condition:   Type 1 Diabetes
Interventions:   Biological: Intranasal insulin;   Other: Placebo
Sponsor:   Melbourne Health
Active, not recruiting - verified May 2015


Improving Metabolic Assessments in Type 1 Diabetes Mellitus Clinical Trials


Condition:   Diabetes Mellitus, Type 1
Interventions:   Procedure: Mixed Meal Tolerance Test;   Procedure: Glucagon Stimulation Test
Sponsors:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   National Institute of Allergy and Infectious Diseases (NIAID);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   Juvenile Diabetes Research Foundation;   National Center for Research Resources (NCRR)
Completed - verified June 2016

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