Join Clinical Trials for Smoking Cessation
While smoking rates have declined nearly 50% in the past 50 years, the National Institute of Drug Abuse has found that 70.9 million Americans over the age of 12 currently use tobacco. This is of particular concern in individuals with mental disease, in which the rate is two to four times higher than the rest of the population.
Clinical trials for smoking cessation is therefore offers many trials to help those suffering from such mental illnesses as depression and posttraumatic stress disorder with smoking cessation. These programs include both behavioral and pharmaceutical interventions, aimed at helping people finally quit their deadly addiction.
To that end, much clinical research is also being conducted to determine what makes this addiction so hard to break. Given the wealth of information available in the media that makes clear just how unhealthy smoking is, there are many who are ready and willing to quit. However, it is incredibly hard to actually commit to quitting for a large portion of those who are addicted.
As a result, there is quite a bit of research attempting to elucidate the genetic component of addiction and smoking cessation. This may even give insight into the efficacy of certain pharmaceuticals based on a person’s genetic makeup.
Another focus is smoking prevention and secondhand smoke exposure prevention. Smoking is the leading cause of preventable death in America, so consider participating in a clinical trial to finally enable you to quit this nasty, deadly addiction.
What will Smoking Cessation Clinical Trials be like?
Your eligibility must first be evaluated during a screening phase to ensure that you are the right fit for the trial. The goal of these trials is often to help those who have been unable to quite smoking and to learn more about the factors behind smoking that make it so hard for many individuals to quit.
The trials are designed to provide participants with some benefit. These criteria are also there to prevent you from experiencing any detrimental pharmaceutical interactions with another medication that you are taking. The researchers will therefore ask you to provide a very detailed medical history.
Clinical trials are also likely to select specific populations, and will thus select participants based upon such criteria. Moreover, they will likely require participants to smoke with a specific daily cigarette-smoking requirement, such as 10 cigarettes per day.
In genetic observational trials, potential participants will be given a genetic assessment to determine if there is any specific mutation present, or to retrospectively assess if there are common traits present within a large population of individuals that are less capable of smoking cessation.
Further blood testing may also be conducted, as well as breathing tests to determine lung capacity. Saliva samples for nicotine level assessments may also be conducted. You may be excluded from participation in interventional trials if you are concomitantly using other pharmacotherapies for smoking cessation.
Typical Smoking Cessation Clinical Trial Protocol:
In smoking cessation trials, if the main interventional method being tested is a new pharmaceutical, then you will likely be randomly assigned to a group that either receives a varying dose of the treatment or a control.
These trials will also often attempt to determine who benefits the most from such smoking cessation programs. Efficacy assessments will then be conducted to evaluate the changes in nicotine levels and smoking habits at certain time points throughout the duration of the trial.
A behavioral intervention trial may conduct a comparative analysis between different forms of exercise, psychotherapy, relaxation, etc. to determine which best facilitates smoking cessation and improves overall health.
Preventative clinical trials for smoking may involve educational programs for children and parents to promote healthy behaviors and prevent kids from smoking or inhaling secondhand smoke.
Other studies might take an observational approach and characterize the population based on health, quality of life, and genetics to perform a longitudinal study on smoking habits and quitting.
You will therefore undergo interviews and questionnaires so that the researchers can create a database from which to draw epidemiologic conclusions. All clinical trials will attempt to provide you personal benefit that improves your quality of life and promotes smoking cessation, while also using information provided by your trial experience to facilitate a decline in the number one cause of preventable deaths in America.
Suggested Search Terms:
“Pharmacotherapies for Smoking Cessation,” “Genetic Contribution to Smoking Cessation,” “Prevention of Second-Hand Smoke,” “Smoking Prevention in Youth,” “Behavioral Interventions for Smoking Cessation,” “Smoking Cessation”
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