About Obesity Clinical Trials (Click to Open)

Join Clinical Trials for Obesity

Clinical Trials for ObesityGeneral Purpose:

Obesity is a major health threat that has become an epidemic in this country. Living with obesity can negatively impact all aspects of your life. It can lead to depression and has an extremely negative impact on an individual’s quality of life.

Obesity cannot simply be attributed to a behavioral issue, as current clinical research is exhibiting the impact of physiology and genetics as contributing factors in causing this excess of body fat. While current interventions help some patients, not all are able to benefit.

Clinical trials for obesity are trying to prevent, treat, and increase the quality of life of those suffering from obesity. Current clinical trials are trying to decipher the effect that genes have on obesity. Studies are also evaluating different interventional methods.

These include surgical, pharmaceutical, and behavioral approaches for the treatment of obesity. Given that obesity affects over 15% of the population under 18 years of age, there are many studies on childhood obesity.

These often include identification and characterization in order to gain a better understanding of the epidemiology of this modern health crisis. If you are struggling with obesity, participating in a clinical trial is an excellent way to take a stand against obesity and make a positive impact on your health.

What will Clinical Trials for Obesity be like?

Your eligibility must first be evaluated during a screening phase to ensure that you are the Clinical Trials for Obesityright fit for the trial. The goal of these trials is to improve the quality of life of those struggling with obesity, so the researchers want to ensure that there is a potential benefit from your participation in the trial.

These criteria are also there to prevent you from experiencing any detrimental pharmaceutical interactions with another medication that you are taking. The researchers will therefore ask you to provide a very detailed medical history. They will also likely give you a clinical assessment of your current health status and determine your BMI, which should be at least 30 for eligibility in most clinical trials for obesity.

In genetic observational trials, potential participants will be given a genetic assessment to determine if there is any specific mutation present, or to retrospectively assess if there are common traits present within a large population of obese individuals enrolled in the trial. Further blood testing may also be conducted.

Typical Obesity Clinical Trial Protocol:

If the main interventional method being tested is a new pharmaceutical, you will be randomly assigned to a group that either receives a varying dose of the treatment or a placebo. If a surgical procedure is part of the treatment, participants will be randomly assigned to a group receiving an interventional surgery, such as gastric band, gastric bypass, or sleeve gastrectomy, for comparison of the benefits and drawbacks.

These trials will also often attempt to determine who benefits the most from such weight loss surgeries, which will typically enroll morbidly obese individuals. Efficacy assessments will then be conducted to evaluate the changes in obesity scores at certain time points after surgery, including potential comparisons between subgroups with co-morbid conditions like type 2 diabetes.  

A behavioral intervention trial may conduct a comparative analysis between two different forms of exercise, such as dance, to determine which best facilitates weight loss and improves health. They would determine this by having specified checkpoints throughout the duration of the study in which they obtain assessments of the treatment’s success, which may assess functional capacities – changes in gait speed, stride length, energy expenditure, etc.

Clinical trials for childhood obesity may involve educational programs for children and parents to promote healthy eating and an active lifestyle. Other studies might take an observational approach and characterize the population based on co-morbidities, quality of life, and SES to perform a longitudinal study on the development of childhood obesity.

All clinical trials will attempt to provide you personal benefit that improves your quality of life, while also using information provided by your trial experience to help cure the obesity epidemic.

Suggested Search Terms:

Childhood Obesity, Morbid Obesity, Genetics of Obesity, Surgical Intervention for Morbidly Obese Individuals, Behavioral Programs for Treating Obesity 

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FITLINE: Pediatric Practice-based Obesity Intervention to Support Families

Condition:   Obesity, Childhood
Interventions:   Behavioral: Coaching;   Behavioral: Materials
Sponsor:   University of Massachusetts, Worcester
Not yet recruiting - verified May 2017

Effects of Brisk Walking on Overweight/Obesity Population

Condition:   Obesity
Intervention:   Behavioral: >10000 steps brisk walking
Sponsor:   Guangdong Center for Disease Prevention and Control
Not yet recruiting - verified April 2017

Kindergarten-based Intervention for Childhood Obesity in Guangzhou(KICOG)

Condition:   Childhood Obesity
Intervention:   Behavioral: Healthy Lifestyles Intervention
Sponsor:   Guangzhou Women and Children's Medical Center
Completed - verified March 2017

Safe and Easy Access Technique for the First Trocar in Laparoscopic Obesity Surgery

Condition:   Obesity, Morbid
Interventions:   Procedure: visual-assisted entry;   Procedure: Veress entry
Sponsor:   Umraniye Education and Research Hospital
Recruiting - verified January 2017

Noninvasive Neuromodulation of the Prefrontal Cortex in Subjects With Obesity

Condition:   Obesity
Interventions:   Device: Active transcranial direct current stimulation (tDCS);   Other: Hypocaloric diet;   Other: Sham transcranial direct current stimulation (tDCS)
Sponsors:   University of Sao Paulo;   Fundação de Amparo à Pesquisa do Estado de São Paulo;   Beth Israel Deaconess Medical Center;   USDA Human Nutrition Research Center on Aging
Not yet recruiting - verified October 2016

Catgut Implantation at Acupoints for the Treatment of Simple Obesity

Condition:   Obesity
Interventions:   Device: Real catgut implantation at acupoints;   Device: sham catgut implantation at acupoints
Sponsors:   Hubei Hospital of Traditional Chinese Medicine;   State Administration of Traditional Chinese Medicine of the People's Republic of China;   Dongzhimen Hospital, Beijing;   The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
Recruiting - verified April 2017

Fecal Microbiota Transplantation for the Treatment of Obesity

Condition:   Obesity
Interventions:   Biological: Fecal Microbiota Transplantation;   Other: Placebo
Sponsor:   Brigham and Women's Hospital
Recruiting - verified February 2017

Probiotics Effect on Glucose and Lipid Metabolism and Gut Microbiota in Patients With Obesity

Condition:   Obesity
Interventions:   Dietary Supplement: Probiotics;   Dietary Supplement: Placebo
Sponsor:   Shanghai 10th People's Hospital
Recruiting - verified March 2017

The Effect of Obesity in Dexmedetomidine Metabolic Clearance

Condition:   Obesity
Intervention:   Drug: Dexmedetomidine
Sponsor:   Pontificia Universidad Catolica de Chile
Active, not recruiting - verified October 2016

Effect of Obesity on Immune Response to Pneumovax 23

Condition:   Obesity
Interventions:   Drug: Pneumovax 23;   Other: Blood tests;   Other: Questionnaires
Sponsor:   University of Florida
Recruiting - verified December 2016

Effect Physical Exercise in Morbid Obesity

Condition:   Morbid Obesity
Interventions:   Other: G1 -Exercise;   Behavioral: G2- Exercise and Lifestyle;   Other: G3- Control
Sponsor:   Hospital de Clinicas de Porto Alegre
Active, not recruiting - verified March 2017

Virtual Sprouts: Web-based Gardening Games to Teach Nutrition and Combat Obesity

Condition:   Obesity
Intervention:   Other: Virtual Sprouts
Sponsors:   University of Southern California;   National Center for Research Resources (NCRR)
Completed - verified March 2017

Study to Investigate Genetic Causes of Severe Early Childhood Onset Obesity.

Condition:   Obesity
Sponsor:   Boston Children’s Hospital
Recruiting - verified September 2016

Pilot Study of Laparoscopic Gastric Plication in Adolescents With Severe Obesity

Condition:   Obesity
Intervention:   Procedure: Laparoscopic Gastric Plication
Sponsors:   Virginia Commonwealth University;   Children's Hospital of Richmond
Recruiting - verified July 2016

Preventing Childhood Obesity Through Early Guidance

Condition:   Childhood Obesity
Intervention:   Other: Education Home Visits
Sponsor:   Arizona State University
Active, not recruiting - verified January 2017

Enoxaparin Dosing in Obesity

Condition:   Obesity
Intervention:   Drug: Enoxaparin
Sponsor:   Emory University
Completed - verified April 2017

For the Health of Our Children--Clinic Based Treatment of Childhood Obesity

Condition:   Obesity
Intervention:   Behavioral: Behavioral counseling
Sponsor:   University of Minnesota - Clinical and Translational Science Institute
Completed - verified January 2017

Deep Brain Stimulation for the Treatment of Obesity

Condition:   Obesity
Intervention:   Device: Deep Brain Stimulation Device
Sponsor:   Ali Rezai, MD
Completed - verified March 2017

Reproductive Hormonal Alterations in Obesity

Condition:   Obesity
Interventions:   Drug: Cetrorelix;   Drug: Gonadorelin-GnRH;   Drug: Recombinant LH;   Drug: Letrozole
Sponsors:   University of Colorado, Denver;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed - verified November 2016

Communicating Risk Information for Obesity

Condition:   Obesity
Interventions:   Genetic: Genetic;   Behavioral: Lifestyle
Sponsors:   Boston University;   National Human Genome Research Institute (NHGRI)
Completed - verified January 2017

Gastrointestinal Hormonal Regulation of Obesity

Condition:   Obesity
Interventions:   Dietary Supplement: Protein powder supplement, standard dosage based on 0.5 gram protein per pound of subject's lean body mass;   Dietary Supplement: Protein powder supplement, High Level Protein, based on 1 gram of protein per pound of lean body mass: 25% protein and 45% carbohydrate;   Dietary Supplement: Very high protein diet group based on 1.4 gram of protein per pound of subject's lean body mass: 35% protein and 35% carbohydrate.
Sponsor:   VA Office of Research and Development
Recruiting - verified January 2017

Brain, Obesity, Dopamine and You Study

Condition:   Obesity
Intervention:   Dietary Supplement: meal replacements, psychotherapy, dietary education
Sponsors:   Washington University School of Medicine;   National Institutes of Health (NIH)
Completed - verified October 2016

Evaluation of High-Density Lipoprotein in Obesity Study

Condition:   Obesity
Sponsor:   The Cleveland Clinic
Terminated - verified April 2017

Translational Obesity Research

Condition:   Obesity
Intervention:   Behavioral: Pathways
Sponsors:   University of Southern California;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed - verified March 2017

Maintenance-Tailored Obesity Treatment

Condition:   Obesity
Interventions:   Behavioral: Standard Behavioral Treatment (SBT);   Behavioral: Maintenance-Tailored Treatment (MTT)
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   University of Washington
Completed - verified February 2017

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3 thoughts on “Obesity

  1. I am an obese woman at the age of 50 I am looking for some help in the Houston, Tx area. I have no insurance. I work a full time job just to survive. I need some help from someone can anyone help me?

      • Hi Melinda , make sure that you fill out a clinical trial profile and include all of you specific information so that clinical trial recruiters can find you.