Heart Disease

About Heart Disease Clinical Trials (Click to Open)

Join Clinical Trials for Heart Disease

Clinical Trials for Heart DiseaseGeneral Purpose:

Heart disease refers to the many diseases affecting the heart. From congenital heart defects to coronary heart disease, there are many ongoing clinical trials for every form of heart disease.

Many forms of heart disease can actually be prevented or treated through behavioral interventions, so there are clinical trials attempting to evaluate prevention and treatment techniques.

There are also trials attempting to determine the prevalence of heart disease within various demographics to gain a better understanding of the epidemiology of this common condition.

Ultimately, clinical trials for heart disease are attempting to improve the quality of life of those afflicted with heart disease and to prevent those with increased risk from developing heart disease.

What will Heart Disease Clinical Trials be like?

Your eligibility must first be evaluated during a screening phase to ensure that you are the right fit for a heart disease trial. The goal of these trials is to improve the quality of life of those with heart disease, so inclusion criteria are intended to provide this benefit and avoid wasting your time.

Inclusion criteria are in place to avoid any risk from detrimental pharmaceutical interactions with another medication that you are taking. The researchers will therefore ask you to provide a very detailed medical history. In preventative trials, participants will be given a screening for heart disease risk factors.

Interventional trials will attempt to determine if you are an appropriate fit for a diverse array of new and improved treatment methods.

Typical Heart Disease Clinical Trial Protocol:

If the main interventional method being tested is a new pharmaceutical, you will be randomly assigned to a group that either receives the treatment or a placebo. To evaluate this intervention, participants will be asked to visit for follow up clinical assessments.Clinical Trials for Heart Disease

Behavioral intervention trials, such as exercise and dietary changes, will assign participants to different groups receiving various treatments or a standard control routine. Throughout the trial each group will be asked to attend follow up visits and testing to evaluate the success of the program.

Baseline measures of heart disease will be taken at the beginning of the trial, such as multi-detector computed tomographic angiography in coronary heart disease, for comparative monitoring purposes during checkpoints in the rest of the trial.

Studies aimed at enhancing the understanding of the various types of heart disease will request many questionnaires about an individual’s health and medical conditions, as well as physical examinations, clinical tests, and interviews.

These studies will help to provide a database of information for researchers to draw conclusions from to help make epidemiologic connections between risk factors and heart disease. Preventative trials will randomly assign participants to a group that will either receive the potential preventative treatment or a placebo.

Your participation in such trials provides critical insight into how this disease develops in at-risk individuals. Participation in all clinical trials for heart disease will enable researchers to improve the lives of those afflicted with heart disease and help prevent heart disease in others.

Suggested Search Terms:

Coronary Heart Disease, Cardiovascular Disease Screening, Genetics of Congenital Heart Defects, Women at Risk for Heart Disease, Exercise and Heart Disease

Current Search Term:

“Heart Disease”

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Genomic Basis of Neurodevelopmental and Brain Outcomes in Congenital Heart Disease (CHD Brain and Genes)


Condition:   Heart Disease Congenital
Interventions:   Other: Exposure of interest: Brain MRI;   Other: Exposure of interest: neurodevelopmental assessments
Sponsors:   Children's Hospital Medical Center, Cincinnati;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting


Valvular Heart Disease Registry Study in Second Affiliated Hospital of ZheJiang University


Condition:   Valvular Heart Disease
Intervention:  
Sponsor:   Second Affiliated Hospital, School of Medicine, Zhejiang University
Not yet recruiting


Assessing Neurodevelopment in Congenital Heart Disease.


Condition:   Congenital Heart Disease
Interventions:   Procedure: Sonography;   Device: Magnetic Resonance Imaging;   Other: Bailey Test;   Procedure: Surgical intervention;   Procedure: Brain monitoring;   Procedure: cord blood sample
Sponsors:   Hospital Universitari Vall d'Hebron Research Institute;   Hospital Sant Joan de Deu;   Hospital Universitario La Paz;   Hospital Universitario 12 de Octubre;   Hospital General Universitario Gregorio Marañon;   Institut Universitari Dexeus
Recruiting


A Partnership to Translate an Evidence-based Intervention (Take Heart) for Vulnerable Older Adults With Heart Disease


Condition:   Heart Diseases
Intervention:   Behavioral: Take Heart
Sponsors:   University of Michigan;   National Institute on Aging (NIA);   Detroit Medical Center;   Detroit Area Agency on Aging
Recruiting


Biventricular Pacing in Children After Surgery for Congenital Heart Disease


Condition:   Congenital Heart Disease (CHD)
Intervention:   Other: Biventricular pacing
Sponsor:   The Hospital for Sick Children
Completed


Study of RV Remodeling in Congenital Heart Disease


Condition:   Congenital Heart Disease
Interventions:   Other: Cardiovascular Magnetic Resonance Imagine (MRI);   Other: Cardiopulmonary exercise testing (CPET);   Other: Echocardiography
Sponsor:   National Heart Centre Singapore
Active, not recruiting


Peri-conception Key Nutritional Factors and Congenital Heart Disease


Condition:   Congenital Heart Disease
Intervention:   Other: observation
Sponsor:   Children's Hospital of Fudan University
Recruiting


Osteopathy and Children With Congenital Heart Disease Surgery


Condition:   Congenital Heart Disease
Interventions:   Other: Osteopathy;   Other: superficial palpatory agreement
Sponsors:   Hôpital Necker-Enfants Malades;   ARCFA : Association for research in cardiology foetal to adult
Completed


Rheumatic Heart Disease Study in Lusaka


Condition:   Rheumatic Heart Disease
Intervention:  
Sponsors:   University of Zambia;   University of Cape Town;   Novartis
Completed


Biventricular Pacing in Children With Congenital Heart Disease


Condition:   Congenital Heart Disease (CHD)
Intervention:   Device: Biventricular Pacing (BiVp)
Sponsor:   The Hospital for Sick Children
Recruiting


Infant Nasal Nitric Oxide Levels in Congenital Heart Disease


Condition:   Congenital Heart Disease
Intervention:   Device: Measurement of nasal Nitric Oxide level
Sponsors:   University of Alberta;   Women and Children's Health Research Institute, Canada
Recruiting


Risk Factors for Acquired Cardiovascular Disease in Adults With Congenital Heart Disease


Condition:   Congenital Heart Disease
Intervention:  
Sponsor:   Stanford University
Enrolling by invitation


Patient NAVIgation to Reduce Readmissions Among Black Men With Heart Disease


Condition:   Heart Diseases
Interventions:   Behavioral: Education + Patient Navigation;   Behavioral: Self-care Education
Sponsor:   University of Alabama at Birmingham
Recruiting


National Congenital Heart Disease Audit


Condition:   Congenital Heart Disease (CHD)
Interventions:   Procedure: Cardiac Surgery;   Procedure: Therapeutic cardiac catheterisations procedures
Sponsors:   University College, London;   Society for Cardiothoracic Surgery in Great Britain & Ireland;   British Congenital Cardiac Association
Recruiting


Accuracy of Peripheral Pulse Oximetry Versus Arterial Co-oximeter in Children With Cyanotic Heart Disease


Condition:   Cyanotic Heart Disease
Intervention:  
Sponsor:   Stanford University
Completed


Assessment of the Efficacy of the First Aspirin Dose in Children Undergoing Surgery for Congenital Heart Disease (CHD) Who Require Post-operative Antiplatelet Therapy


Condition:   Congenital Heart Disease
Intervention:  
Sponsor:   University of Colorado, Denver
Active, not recruiting


Efficacy of Remodulin in Adults With Congenital Heart Disease (ACHD) and Pulmonary Hypertension


Condition:   Congenital Heart Disease
Intervention:   Drug: Remodulin
Sponsors:   University of California, Los Angeles;   United Therapeutics
Withdrawn


The Genetic Basis of Congenital Heart Disease in Africa


Conditions:   Congenital Heart Disease;   Heart Disease
Intervention:  
Sponsors:   National Human Genome Research Institute (NHGRI);   University of Lagos, Nigeria;   Uganda Heart Institute, Kampala, Uganda
Recruiting


Synbiotics in Infants With Cyanotic Congenital Heart Disease


Condition:   Congenital Heart Disease
Interventions:   Dietary Supplement: Bifidobacterium lactis plus inulin;   Dietary Supplement: Maltodextrin
Sponsor:   Dr. Sami Ulus Children's Hospital
Completed


The Impact of Implementing a Universal Newborn Screening for Critical Congenital Heart Disease


Condition:   Congenital Heart Disease
Intervention:  
Sponsor:   Mednax Center for Research, Education and Quality
Completed


Myocardial Perfusion and Scarring in Congenital Heart Disease


Condition:   Congenital Heart Disease
Intervention:  
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   Children's Research Institute;   Suburban Hospital
Completed


Rheumatic Heart Disease School Project


Condition:   Rheumatic Heart Disease
Intervention:  
Sponsors:   University Hospital Inselspital, Berne;   B.P. Koirala Institute of Health Sciences
Recruiting


Genetics of Congenital Heart Disease


Condition:   Congenital Heart Disease
Intervention:   Other: Blood Sample Collection
Sponsors:   Nationwide Children's Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting


Parenteral Phenoxybenzamine During Congenital Heart Disease Surgery


Condition:   Congenital Heart Disease
Interventions:   Drug: Phenoxybenzamine;   Other: Standard surgical approach
Sponsor:   Vanderbilt University
Withdrawn


Prenatal Effects of Congenital Heart Disease (CHD) on Neurodevelopmental Outcome


Condition:   Congenital Heart Disease
Intervention:  
Sponsor:   Columbia University
Completed

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