Healthy Volunteers



The Tolerance, Pharmacokinetics of Jaktinib in Healthy Volunteers


Condition:   Healthy Volunteers
Interventions:   Drug: Jaktinib Dihydrochloride Monohydrate;   Drug: placebo
Sponsor:   Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Recruiting


AZD1390 Administration of a Microdose [11C]AZD1390 to Healthy Volunteers


Condition:   Healthy Volunteer Male Subjects
Intervention:   Drug: [11C]AZD1390
Sponsors:   AstraZeneca;   Karolinska Institutet, Quintiles IMS
Recruiting


Safety of Prasaprohyai 95%Ethanolic Extract Capsules in Healthy Volunteer


Condition:   Healthy Volunteers
Intervention:   Drug: Prasaprohyai
Sponsors:   Thammasat University;   Thai Traditional Medical Knowledge Fund
Not yet recruiting


A Phase 1 Bioavailability Study of Arbaclofen Placarbil Modified Release Formulations in Healthy Volunteers


Condition:   Healthy Volunteers
Interventions:   Drug: Arbaclofen Placarbil SR;   Drug: Arbaclofen Placarbil MR Prototype A;   Drug: Arbaclofen Placarbil MR Prototype B;   Drug: Arbaclofen Placarbil IR
Sponsor:   Indivior Inc.
Completed


A First-In-Human Study With a Single Dose UCB4019 in Healthy Volunteers


Condition:   Healthy Volunteers
Interventions:   Drug: PR1;   Other: PL1
Sponsor:   UCB Biopharma S.P.R.L.
Completed


Prolonged Hypoxic Breathing in Healthy Volunteers: a Safety Study


Condition:   Healthy Volunteers
Intervention:   Drug: Inhaled Nitrogen
Sponsors:   Massachusetts General Hospital;   Rezoagli, Emanuele, M.D., Massachusetts General Hospital, Harvard Medical School;   Ferrari, Michele, M.D., Massachusetts General Hospital, Harvard Medical School;   Patel, Sarvagna, B.A., Massachusetts General Hospital, Harvard Medical School;   Zapol, Warren M., M.D., Massachusetts General Hospital, Harvard Medical School;   Fisher, Daniel, R.R.T., Massachusetts General Hospital, Harvard Medical School;   Jain, Isha, B.A., Massachusetts General Hospital, Harvard Medical School;   Mootha, Vamsi, M.D., Massachusetts General Hospital, Harvard Medical School;   Harris, Stuart N., M.D., Massachusetts General Hospital, Harvard Medical School;   Karaa, Amel, M.D., Massachusetts General Hospital, Harvard Medical School
Recruiting


A Study to Assess the Relative Bioavailability And Food Effect of a Tablet Formulation of GDC-0276 in Healthy Participants


Condition:   Healthy Volunteer
Interventions:   Drug: GDC-0276 capsule;   Drug: GDC-0276 tablets
Sponsor:   Genentech, Inc.
Withdrawn


Single Ascending Dose Study to Evaluate Pharmacokinetics and Food-Effect in Healthy Volunteers


Condition:   Healthy Volunteers
Intervention:   Drug: ASN002
Sponsor:   Asana BioSciences
Completed


Safety, Tolerability, PK of Oral NYX-2925 in Healthy Volunteers


Condition:   Healthy Volunteers
Intervention:   Drug: NYX-2925
Sponsors:   Aptinyx;   Spaulding Clinical Research LLC
Completed


A Study of HMPL-689 in Healthy Volunteers


Condition:   Healthy Volunteers
Interventions:   Drug: HMPL-689;   Drug: HMPL-689 placebo
Sponsor:   Hutchison Medipharma Limited
Completed


A Study to Investigate Safety, Tolerability, and Pharmacokinetics of DSTA4637S in Healthy Volunteers


Condition:   Healthy Volunteer
Interventions:   Drug: DSTA4637S;   Drug: Placebo
Sponsor:   Genentech, Inc.
Completed


Food Effect and Bioavailability of Deflazacort Formulations in Healthy Volunteers


Condition:   Healthy Volunteers
Intervention:   Drug: Deflazacort
Sponsors:   PTC Therapeutics;   ICON Development Solutions
Completed


A Quantitative Optical Sensor to Monitor Vascular Physiology; A Healthy Volunteer Study


Condition:   Healthy Volunteer
Intervention:  
Sponsor:   Zenalux Biomedical, Inc.
Completed


A Study of High Dose MHAA4549A in Healthy Volunteers


Condition:   Healthy Volunteer
Interventions:   Drug: MHAA4549A;   Drug: Placebo
Sponsor:   Genentech, Inc.
Completed


AZD8108 SAD/MAD in Healthy Volunteers


Condition:   Healthy Volunteers
Interventions:   Drug: AZD8108;   Drug: Placebo
Sponsor:   AstraZeneca
Completed


Safety and Pharmacokinetics Study of Redosing EXPAREL in Healthy Volunteers


Condition:   Healthy Volunteers
Intervention:   Drug: EXPAREL
Sponsor:   Pacira Pharmaceuticals, Inc
Completed


A Study of MHAA4549A in Healthy Volunteers in an Influenza Challenge Model


Condition:   Healthy Volunteer
Interventions:   Drug: MHAA549A;   Drug: Placebo;   Drug: oseltamivir [Tamiflu]
Sponsor:   Genentech, Inc.
Completed


Functional Brain Imaging in Healthy Volunteers to Study Cognitive Functions


Condition:   Healthy Volunteers
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting


Open Label Phase 1 Pharmacokinetics and Tolerability Study of Single TAB08 Administration in Healthy Volunteers


Condition:   Adult Healthy Volunteers
Intervention:   Biological: TAB08
Sponsor:   Theramab LLC
Completed


Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests


Condition:   Healthy Volunteers
Interventions:   Biological: PRT064445;   Biological: Placebo
Sponsor:   Portola Pharmaceuticals
Completed


ANX-042 Healthy Volunteer Dose Escalation Study


Condition:   Healthy Volunteers
Interventions:   Drug: ANX-042;   Drug: Placebo
Sponsors:   Mayo Clinic;   Anexon, Incorporated;   Celerion
Completed


A Study of LY3016859 in Healthy Volunteers


Condition:   Healthy Volunteers
Interventions:   Drug: LY3016859 IV;   Drug: Placebo IV;   Drug: LY3016859 SC;   Drug: Placebo SC
Sponsor:   Eli Lilly and Company
Completed


Effects of Rosuvastatin on the Immune System in Healthy Volunteers With Normal Cholesterol


Condition:   Healthy Volunteers
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed


Collection of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Laboratory Research Studies


Condition:   Healthy Volunteers
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Suspended


Study to Evaluate Single Inhaled Doses of PT001, PT003, PT005 and PT001 Plus PT005 in Healthy Subjects


Condition:   Healthy Volunteers
Interventions:   Drug: PT001;   Drug: PT005;   Drug: PT003;   Drug: PT001 + PT005
Sponsor:   Pearl Therapeutics, Inc.
Completed

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