Fibromyalgia

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Fibromyalgia Clinical Trials

General Purpose:

Living with fibromyalgia entails living in constant pain. This common syndrome can affect the entire body, making it a challenge to perform basic activities of daily living. Clinical research is therefore attempting to improve the quality of life of those afflicted with fibromyalgia.

Though the exact cause of fibromyalgia has yet to be uncovered, evidence suggests the involvement of the central nervous system. As a result, many clinical trials intend to enhance the understanding of this syndrome, as well as its diagnosis.

Clinical research is also working relentlessly to improve the painful symptoms associated with fibromyalgia, through a diverse array of interventional methods. If you are suffering from fibromyalgia, participating in a clinical trial is an excellent way to find an improved approach to living well with this syndrome and to positively impact the lives of others who are also living with fibromyalgia.

What will  Fibromyalgia Clinical Trials be like?

Clinical trials for fibromyalgia will conduct screenings of each potential participant, which may include a physical exam, medical history, and clinical assessment based on the 1990 American College of Rheumatology (ACR) diagnostic criteria for fibromyalgia. Depending on the specific trial, the study doctor may request additional tests for each individual.

The goal is to ensure that you are the proper fit for a trial. Researchers understand the great burden of living with fibromyalgia, so they aim to select participants that will gain a benefit from taking part in the trial, ideally for both them and other patients struggling with this detrimental condition.

Since the cause of fibromyalgia remains unclear and there is no completely effective treatment available, there is an extensive range of interventional methods beings evaluated. As a result, you must make sure to pick a clinical trial that you feel comfortable participating in after reading the informed consent and learning about what it will entail.

Inclusion criteria are intended to provide benefit and avoid wasting your time. They are also put in place to avoid any risk, which could result if, for example, the trial were assessing a new pharmaceutical treatment that had detrimental interactions with another medication that you are taking. Moreover, you should consult with your current physician if you are unsure about getting involved.

Typical Fibromyalgia Clinical Trial Protocol:

Given the imprecise understanding of this condition and the lack of a completely effectiveFibromyalgia clinical trials treatment, different trial protocols may vary greatly. Regarding interventional studies, treatment methods may vary from exercise to an alternative medicine approach. Ultimately, most interventional studies will randomly assign you to a group. In this group you will participate in a treatment or a control for comparison.

A behavioral intervention trial may conduct a comparative analysis between two different forms of exercise to determine which best manages pain and improves functioning. In other words, the trial will attempt to determine the most effective intervention for improving the fibromyalgia symptoms that impact your quality of life.

They would determine this by having specified checkpoints throughout the duration of the study in which they obtain assessments of the treatment’s success, which may simply require a questionnaire.

They may also attempt to determine the optimal frequency and duration of such behavioral interventions by further splitting participants up into different treatment specifications. Other studies might follow a similar outline, but instead the treatment may involve a pharmaceutical, a supplement, a current stimulation, etc.

Trials intending to expand the knowledge base of fibromyalgia may include an improved diagnostic measure, such as MRI, to make observations about the manifestations of this condition.

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Exercise and Fibromyalgia, Fibromyalgia Pain Management, Acupuncture and Fibromyalgia, Female Fibromyalgia Study, Tai Chi for Reducing Fibromyalgia Pain

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Membrane Lipid Replacement in Fibromyalgia


Condition:   Fibromyalgia
Interventions:   Dietary Supplement: NTFactor Lipids®;   Dietary Supplement: Placebo
Sponsor:   Institute for Molecular Medicine
Recruiting


Community-based Intervention for Fibromyalgia: A Pilot Trial


Condition:   Fibromyalgia
Intervention:   Other: Multidisciplinary intervention
Sponsors:   University of British Columbia;   Canadian Rheumatology Association;   Interior Health
Not yet recruiting


Evaluate the Efficacy and Safety of NYX-2925 in Subjects With Fibromyalgia


Condition:   Fibromyalgia
Interventions:   Drug: NYX-2925;   Drug: Placebo oral capsule
Sponsors:   Aptinyx;   inVentiv Health Clinical
Recruiting


Postural Exercises in Women With Fibromyalgia


Condition:   Fibromyalgia
Interventions:   Other: Low impact aerobic exercise;   Other: Postural exercises
Sponsor:   University of Valencia
Recruiting


Mat Pilates Method in the Treatment of Women With Fibromyalgia


Condition:   Fibromyalgia, Primary
Interventions:   Other: Mat Pilates exercises;   Other: Aquatic aerobic exercises
Sponsor:   Universidade Federal do Rio Grande do Norte
Recruiting


Impact of the Restriction of Sources of Gluten in Fibromyalgia Patients


Condition:   Fibromyalgia
Interventions:   Dietary Supplement: Gluten;   Dietary Supplement: Rice protein
Sponsor:   Federal University of Minas Gerais
Completed


A Study to Assess the Analgesic Efficacy and Safety of ASP8062 in Subjects With Fibromyalgia


Condition:   Fibromyalgia
Interventions:   Drug: ASP8062;   Drug: Placebo
Sponsor:   Astellas Pharma Global Development, Inc.
Recruiting


A Study to Assess the Analgesic Efficacy and Safety of ASP0819 in Patients With Fibromyalgia


Condition:   Fibromyalgia
Interventions:   Drug: ASP0819;   Drug: Placebo
Sponsor:   Astellas Pharma Global Development, Inc.
Recruiting


Effects of Pain Neuroscience Education in Fibromyalgia


Condition:   Fibromyalgia
Interventions:   Other: Pain neuroscience education + Exercise;   Other: Exercise
Sponsor:   University of Malaga
Not yet recruiting


Development of a Mobile Application to Promote Self-care in Patients With Fibromyalgia


Condition:   Fibromyalgia
Interventions:   Device: ProFibro (Mobile application);   Device: Paper booklet
Sponsors:   University of Sao Paulo General Hospital;   Fundação de Amparo à Pesquisa do Estado de São Paulo
Recruiting


Home-based Transcranial Direct Current Stimulation in Fibromyalgia Patients


Condition:   Fibromyalgia
Interventions:   Other: Active-tDCS;   Other: Sham-tDCS
Sponsor:   Wolnei Caumo
Recruiting


Prospective Evaluation of RINCE to Reduce Fibromyalgia Effects - 202


Condition:   Fibromyalgia
Intervention:   Device: RINCE
Sponsor:   Cerephex Corporation
Completed


Lu Eight Brocades for Treating Patients With Fibromyalgia


Condition:   Fibromyalgia
Intervention:   Behavioral: The Lu Eight Brocades
Sponsors:   Guang'anmen Hospital of China Academy of Chinese Medical Sciences;   Beijing Municipal Science & Technology Commission
Completed


Dance-movement Therapy Programme in Fibromyalgia.


Condition:   Fibromyalgia
Interventions:   Other: Dance-movement therapy;   Other: Control group
Sponsor:   Universidad de Granada
Recruiting


Pain Sensitivity of Subjects With Fibromyalgia Before and After Repetitive Transcranial Magnetic Stimulation Treatment


Condition:   Fibromyalgia
Intervention:   Other: experimental pain induction
Sponsor:   Centre Hospitalier Esquirol
Completed


Fibromyalgia Activity Study With Transcutaneous Electrical Nerve Stimulation (FAST)


Condition:   Fibromyalgia
Intervention:   Device: TENS
Sponsors:   University of Iowa;   Vanderbilt University
Recruiting


Neurodynamic Intervention in Fibromyalgia


Condition:   Fibromyalgia
Interventions:   Other: Neurodynamic technique group;   Other: Placebo group
Sponsor:   Universidad de Granada
Completed


Novel Use of (Oral) Ketotifen for the Treatment of Fibromyalgia: A Pilot Study


Condition:   Fibromyalgia
Interventions:   Drug: Ketotifen;   Drug: Placebo (Sugar Pill)
Sponsor:   Indiana University
Completed


A Study For Pregabalin In Patients With Fibromyalgia


Condition:   Fibromyalgia
Interventions:   Drug: pregabalin;   Drug: placebo
Sponsor:   Pfizer
Completed


Effect of Milnacipran on Pain in Fibromyalgia


Condition:   Fibromyalgia
Intervention:   Drug: Milnacipram
Sponsors:   University of California, San Diego;   Forest Laboratories;   VA Office of Research and Development
Completed


A Study of Duloxetine in Adolescents With Juvenile Primary Fibromyalgia Syndrome


Condition:   Fibromyalgia
Interventions:   Drug: Duloxetine;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Active, not recruiting


Study of Mattress Type in Fibromyalgia


Condition:   Fibromyalgia
Interventions:   Other: Tempur-Pedic Mattress (2 months);   Other: Control Mattress (2 months)
Sponsor:   Beth Israel Medical Center
Completed


Transcutaneous Electrical Nerve Stimulation (TENS) and Fibromyalgia (FM)


Condition:   Fibromyalgia
Interventions:   Device: Transient Placebo TENS (Rehabilicare Maxima TENS);   Device: Active TENS (Rehabilicare Maxima TENS);   Device: No TENS (Rehabilicare Maxima TENS)
Sponsors:   University of Iowa;   American Physical Therapy Association
Unknown status


Neurotropin to Treat Fibromyalgia


Condition:   Fibromyalgia
Intervention:   Drug: Neurotropin
Sponsor:   National Institute of Nursing Research (NINR)
Completed


Optimizing Fibromyalgia Self-management


Condition:   Fibromyalgia
Interventions:   Behavioral: Aerobic;   Behavioral: Strength training;   Behavioral: Combination;   Behavioral: FSHC
Sponsors:   Beth Israel Deaconess Medical Center;   Arthritis Foundation;   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Completed

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