Diabetes (Type 2)

About Diabetes (Type 2) Clinical Trials (Click to Open)

Join Clinical Trials for Diabetes Type 2

General Purpose:

Clinical Trials for Diabetes Type 2Living with Type 2 Diabetes results in a constant struggle to manage blood glucose levels. As a result, clinical research is attempting to find new and improved ways to live well with this chronic disease.

Given the necessity of lifestyle changes upon diagnosis, there are many clinical trials attempting to find the most effective behavioral interventions. Interventional trials of this nature will evaluate different behavioral programs related to standard diabetes counseling.

They will assess glycemic control and weight in participants to evaluate the programs. Other trials may evaluate the benefit of pharmaceutical interventions, potentially in conjunction with, or in comparison to, behavioral intervention.

In severely obese patients, clinical trials may perform laparoscopic adjustable gastric band surgery or gastric bypass surgery, to potentially improve metabolic control and treat type 2 diabetes.

These surgeries can provide life-changing results by improving insulin action beyond that of weight loss alone. Given the dire health threat presented by type 2 diabetes in extremely obese individuals, participation in interventional clinical trials can be incredibly beneficial to the future of your health.

As the main goal of this clinical research is to improve the quality of life of those living with diabetes, there are also trials dedicated to improving/facilitating blood sugar monitoring. Other studies are attempting to decipher risk factors for developing type 2 diabetes. These may include genetic and behavioral risk factors.

What will Clinical Trials for Diabetes Type 2 be like?

Before joining a clinical trial, researchers will first assess your eligibility. You will go through a screening phase to ensure that you are an appropriate participant for the aims of the trial.

The goal of these trials is to improve the quality of life of those with Type 2 Diabetes, so Clinical Trials for Diabetes Type 2inclusion criteria are intended to provide this benefit and avoid wasting your time. They are also put in place to avoid any risk of a detrimental interaction between a behavioral or pharmaceutical intervention and an existing condition or medication.

The researchers will therefore ask you to provide a very detailed medical history. Preventative trials will first require participants to undergo in depth screening, including serum glucose and other fasting blood tests. Interventional trials will assess your diagnoses to determine if you are a good candidate for surgical intervention, behavioral, pharmaceutical, etc.

Typical Trial Protocol:

If the main interventional method being tested is a new pharmaceutical, you will be randomly assigned to a group that either receives a varying dose of the treatment or a placebo.

Clinical Trials for Diabetes Type 2If a surgical procedure is part of the treatment, participants will be randomly assigned to a group receiving an interventional surgery, such as gastric band or gastric bypass, in comparison to groups that receive medical and weight management.

They will then receive follow-up assessments of glycemic index, metabolic factors, cardiovascular risk, and quality of life at specified time points after the treatment.

To evaluate this intervention, participants will be asked to visit for follow up physical examinations, blood tests, and urine collection. While participating in these interventional studies, you will receive care and your glucose monitoring, though you may be unable to participate in other studies to avoid detrimental interactions between trial treatments.

Studies conducted to evaluate the clinical utility of risk assessment measures will randomly assign eligible individuals to different risk assessment groups, which may include genetic testing.

Given the impact of behavior on type 2 diabetes, participants will undergo relevant baseline assessments, such as BMI, waist circumference, fasting plasma glucose and insulin.

After receiving counseling about their individual risk, they will return for follow up assessments to determine the effect that this risk information plays on a person’s perception of risk. This will be analyzed through the assessment of resulting behavioral changes made to diet and exercise.

All clinical trials will attempt to provide you personal benefit that improves your quality of life, while also using information provided by your trial experience for the betterment of all diabetic individuals.

Suggested Search Terms:

Type 2 Diabetes and Obesity, Type 2 Diabetes and Blood Glucose Management, Weight loss Programs for Type 2 Diabetes, Type 2 Diabetes Prevention, Risk Assessment for Type 2 Diabetes

Current Search Term Used: “Diabetes Type 2″



Effect of Holistic Management on the Patients With Type 2 Diabetes


Condition:   Type 2 Diabetes Mellitus
Interventions:   Behavioral: short-term intensive education;   Behavioral: Holistic management
Sponsor:   Cheng Qing-feng
Not yet recruiting


Basal-bolus Insulin Therapy Versus Standard Therapy for the Inpatient Management of Type 2 Diabetes: the IDA2 Study


Condition:   Type 2 Diabetes Mellitus
Intervention:   Drug: Insulin Degludec 100 UNT/ML [Tresiba]
Sponsors:   Merete Bechmann Christensen;   Novo Nordisk A/S
Recruiting


A Study to Evaluate the Effect of BioK+ 50B® on Glycemic Control in a Type 2 Diabetes Population


Condition:   Type2 Diabetes
Interventions:   Other: BioK+ 100% probiotic;   Other: Placebo
Sponsors:   Bio-K Plus International Inc.;   Montreal Heart Institute
Not yet recruiting


The Effectiveness of Low Carbohydrate Diet in Reducing Polypharmacy for Patients With Type 2 Diabetes Mellitus


Condition:   Type 2 Diabetes Mellitus
Interventions:   Dietary Supplement: Low carbohydrate diet;   Dietary Supplement: Calori restricted diet
Sponsor:   National Taiwan University Hospital
Active, not recruiting


Person-centred Interactive Self-management Support in Primary Healthcare for People With Type 2 Diabetes


Condition:   Diabetes Type 2
Interventions:   Behavioral: Intervention arm: Person-centred interactive self-management support;   Other: Control arm;   Other: External comparison group
Sponsors:   Umeå University;   The Swedish Diabetes Foundation;   The County Council of Västerbotten
Recruiting


A Dose Finding Study to Assess the Effect of LIK066 Compared to Placebo or Empagliflozin in Patients With Type 2 Diabetes Mellitus and Heart Failure


Condition:   Diabetes Type 2 With Heart Failure
Interventions:   Drug: LIK066;   Drug: Placebo;   Drug: Empagliflozin
Sponsor:   Novartis Pharmaceuticals
Recruiting


Usage of Dapagliflozin in the Management of Type-2 Diabetes Mellitus: A Real World Evidence Study in Indian Patients


Condition:   Type 2 Diabetes
Intervention:  
Sponsor:   AstraZeneca
Recruiting


The Application of the E-health Education on Shared Care Program for Patients With Type 2 Diabetes


Condition:   Type 2 Diabetes Mellitus
Interventions:   Behavioral: E-health Education;   Other: Routine care
Sponsor:   Li-Li Chen
Recruiting


Economic Outcomes of EQW (Exenatide Once Weekly) vs. IG (Insulin Glargine) in T2D Patients Who Are New to Injectable Therapy


Condition:   Diabetes Mellitus Type 2
Intervention:  
Sponsors:   AstraZeneca;   Truven health
Completed


Mineralocorticoid Receptor Antagonists in Type 2 Diabetes


Condition:   Diabetes Type 2
Interventions:   Drug: Eplerenone;   Drug: Placebo
Sponsor:   Herlev Hospital
Active, not recruiting


Effect of Periodontal Therapy in the Systemic Status of Individuals With Chronic Periodontitis and Diabetes Type 2


Conditions:   Chronic Periodontitis;   Diabetes Type 2
Interventions:   Device: Mechanical periodontal therapy;   Procedure: nonsurgical periodontal therapy
Sponsors:   University of Brasilia;   Catholic University of Brasília;   Brasilia University Hospital
Active, not recruiting


Effects of Prebiotics on GLP-1 in Type 2 Diabetes


Condition:   Diabetes Type 2
Interventions:   Dietary Supplement: Prebiotic fibers: oligofructose and inulin;   Dietary Supplement: Maltodextrin
Sponsors:   Oslo University Hospital;   Norwegian Diabetes Association;   Norwegian Extra Foundation for Health and Rehabilitation
Recruiting


Phase II Safety and Efficacy Study of Oral ORMD-0801 in Patients With Type 2 Diabetes Mellitus


Condition:   Diabetes Type 2
Interventions:   Drug: ORMD-0801;   Drug: Placebo Comparator
Sponsors:   Oramed, Ltd.;   Integrium
Completed


DISCOVERing Treatment Reality of Type 2 Diabetes in Real World Settings


Condition:   Type 2 Diabetes Mellitus
Intervention:  
Sponsor:   AstraZeneca
Active, not recruiting


DISCOVERing Treatment Reality of Type 2 Diabetes in Real World Setting in Japan


Condition:   Type 2 Diabetes Mellitus
Intervention:  
Sponsors:   AstraZeneca;   Ono Pharmaceutical Co. Ltd
Active, not recruiting


Study of Chiglitazar Compare With Placebo in Type 2 Diabetes Patients


Condition:   Type 2 Diabetes
Interventions:   Drug: Chiglitazar;   Drug: Placebo
Sponsor:   Chipscreen Biosciences, Ltd.
Active, not recruiting


Diet and Exercise Intervention in Type 2 Diabetes


Condition:   Type 2 Diabetes
Interventions:   Behavioral: Optimum Lifestyle Intervention;   Behavioral: Standard Care
Sponsors:   Washington University School of Medicine;   National Dairy Council;   American Egg Board
Completed


Provider-Initiated Regular Remote Interventions for Optimal Type 2 Diabetes Care


Condition:   Type 2 Diabetes
Interventions:   Other: Remote, personalized type 2 diabetes care.;   Other: Usual Endocrine care.
Sponsor:   University of Michigan
Active, not recruiting


Postpartum Screening of Type 2 Diabetes


Condition:   Type 2 Diabetes
Intervention:   Procedure: oral glucose tolerance test 2 days post-partum
Sponsors:   Université de Sherbrooke;   The Lawson Foundation
Active, not recruiting


Early add-on Vildagliptin in Patients With Type 2 Diabetes Inadequately Controlled by Metformin


Condition:   Type-2 Diabetes Mellitus
Interventions:   Drug: LAF237 (vildagliptin);   Drug: Metformin
Sponsor:   Novartis Pharmaceuticals
Completed


Early Intermittent Intensive Insulin Therapy as an Effective Treatment of Type 2 Diabetes (RESET-IT Pilot Study)


Condition:   Type 2 Diabetes
Interventions:   Drug: Intermittent insulin therapy;   Drug: Continuous metformin
Sponsors:   Mount Sinai Hospital, Canada;   Canadian Institutes of Health Research (CIHR)
Active, not recruiting


Safety and Efficacy of Vildagliptin Versus NPH Insulin add-on to Glimepiride in Type 2 Diabetes Mellitus Patients.


Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: LAF237;   Drug: Protaphane
Sponsor:   Novartis Pharmaceuticals
Completed


Exercise Study on Cardiac Function in Patients With Diabetes Mellitus Type 2 and Diastolic Dysfunction


Condition:   Diabetes Type 2
Intervention:   Other: Exercise
Sponsor:   Norwegian University of Science and Technology
Completed


A Study to Evaluate the Safety and Efficacy of Sitagliptin 100 mg in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control (MK-0431-229)


Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Sitagliptin phosphate;   Drug: Comparator: placebo to pioglitazone;   Drug: Comparator: placebo to Sitagliptin;   Drug: Comparator: pioglitazone;   Drug: Glimepiride or gliclazide;   Drug: Metformin;   Drug: Pioglitazone rescue therapy
Sponsor:   Merck Sharp & Dohme Corp.
Completed


Effect of DMMET-01 on Insulin Sensitivity in Naive Type 2 Diabetes Patients (CLAMP)


Condition:   Diabetes Type 2
Interventions:   Drug: DMMET-01;   Drug: Placebo
Sponsor:   Laboratorios Silanes S.A. de C.V.
Completed

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