Chronic Pain

About Chronic Pain Clinical Trials (Click to Open)

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Clinical Trials for Chronic PainGeneral Purpose:

Living with chronic or acute pain can negatively impact all aspects of your life. Clinical trials for chronic pain are trying to improve the quality of life of those struggling to make it through each day despite their debilitating condition.

Current clinical trials are therefore trying to determine the safety and efficacy of interventional treatment methods for pain management. These range from medications and analgesics to acupuncture. Trials will also assess the benefit of different behavioral interventions, such as chronic pain group therapy.

In addition to interventional trials, there are also many observational trials intending to develop new techniques to characterize the physiological changes that are indicative of both chronic and acute pain.

Clinical trials for chronic pain will enhance the scientific body of knowledge surrounding the negative impact that pain has on its sufferers, thereby enhancing the ability of science to treat it.  

What will Clinical Trials for Chronic Pain be like?

Clinical trials for pain will conduct assessments of each potential participant’s pain rating, generally determined based on a numerical rating scale value greater than 3. This may include a physical exam and detailed medical history.

You will be asked to report on your painful symptoms, which may include information regarding a surgery with moderate to severe pain, extremity bone fracture, a somatosensory disease, etc.

Researchers understand the impedance of living with depression, so they aim to select participants that will gain a benefit from taking part in the trial, ideally for them and other patients struggling with this detrimental condition.

Inclusion criteria are intended to provide benefit and avoid wasting your time. The goal is to ensure that you are the proper fit for a trial and to reduce any potential risk.

Typical Pain Clinical Trial Protocol:

Pharmaceutical intervention trials will start by first randomly assigning participants to a Clinical Trials for Chronic Paingroup that either receives a varying dose of the treatment or a placebo. You will then be asked to report on your symptoms so that potential benefit can be evaluated.

In chronic pain therapy trials, comparison will be made between the self-reported baseline measurements, which might include anything from physical to emotional functioning, and specified time point assessments taken throughout the trial.

Acute pain trials will follow a similar outline. You should also note that as with any clinical trial, it is possible that you will be randomly selected for the placebo group. You would therefore undergo the same procedures as the treatment group without receiving the actual treatment being tested.

If it is a behavioral intervention trial, participants will be assigned to a group receiving the behavior or a control to evaluate the benefit of the treatment method. Participants will then receive questionnaires to assess the efficacy of the program, quality of life evaluation, health care utilization, and further outcome measures dependent on the specific pain trial.

The ultimate goal of clinical trials for chronic pain is to benefit those suffering from acute and chronic pain, so all trials will work relentlessly to meet that end.

Suggested Search Terms:

Chronic Pain Management, Pain Relief after Acute Injury, Chronic Pain Group Therapy, Alternative Medicine Approach to Pain Treatment, Analgesics for Pain Treatment

Current Search Term:

“Chronic Pain”

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Nature as a Buffer Among People With Chronic Pain

Condition:   Chronic Pain
Interventions:   Other: Natural Environment;   Other: Built Environment
Sponsor:   Cornell University
Active, not recruiting - verified May 2017

Adaptation of Mindfulness Training to Treat Chronic Pain in the Military

Condition:   Chronic Pain
Intervention:   Behavioral: Mindfulness Training
Sponsors:   RTI International;   University of North Carolina, Chapel Hill
Recruiting - verified May 2017

Internet-delivered ACT for Chronic Pain

Condition:   Chronic Pain
Interventions:   Behavioral: Internet delivered Acceptance and Commitment therapy;   Behavioral: Waiting list control condition
Sponsors:   Rikard Wicksell;   AFA Insurance
Recruiting - verified April 2017

Impact of Lifestyle Changes on Telomeric Activity in Patients With Chronic Pain

Condition:   Chronic Pain
Intervention:   Behavioral: The Complete Health Improvement Program
Sponsor:   Ohio University
Enrolling by invitation - verified February 2017

Chronic Pain, Life Style Factors and Quality of Life

Condition:   Chronic Pain
Sponsor:   Helsinki University Central Hospital
Completed - verified January 2017

The Use of Resting State, fMRI and DTI in the Identification of Chronic Pain Conditions

Condition:   Chronic Pain
Sponsors:   Brain Scan Inc.;   State University of New York at Buffalo
Recruiting - verified December 2016

Social & Behavioral Rhythms in Chronic Pain

Condition:   Chronic Pain
Interventions:   Behavioral: Interpersonal Social Rhythms Psychotherapy;   Device: Bright Light Device
Sponsor:   University of Utah
Recruiting - verified January 2017

Chronic Pain and Assessment of Sleep

Condition:   Chronic Pain
Intervention:   Other: Sleep assessment tools
Sponsors:   University of Aberdeen;   NHS Grampian
Completed - verified January 2017

Our Whole Lives: Online Chronic Pain Management

Condition:   Chronic Pain
Intervention:   Behavioral: Our Whole Lives Website
Sponsors:   Boston Medical Center;   Aetna, Inc.
Recruiting - verified January 2017

Improving the Management of Chronic Pain in Primary Care

Condition:   Chronic Pain
Intervention:   Behavioral: Photo-elicitation and online group support
Sponsors:   University of Missouri-Columbia;   American Academy of Family Physicians National Research Network
Recruiting - verified October 2016

Objective Pain Score for Chronic Pain Clinic Patients

Condition:   Chronic Pain
Intervention:   Behavioral: Pain Assessment
Sponsor:   Milton S. Hershey Medical Center
Recruiting - verified October 2016

Multidisciplinary Group Based Treatment of Patients With Chronic Pain

Condition:   Chronic Pain
Intervention:   Behavioral: Acceptance and Commitment Therapy
Sponsors:   University of Tromso;   The Royal Norwegian Ministry of Health
Recruiting - verified September 2016

The Chronic Pain Incidence After Elective and Urgent Cesarean Sections

Condition:   Chronic Pain
Sponsor:   Tokat Gaziosmanpasa University
Completed - verified April 2017

Mobile Phone Technology for Chronic Pain Patients- A Feasibility Study

Condition:   Chronic Pain
Interventions:   Other: Electronic Diary;   Other: Questionnaire
Sponsor:   Weill Medical College of Cornell University
Recruiting - verified February 2017

Chronic Pain Self-management Support With Pain Education and Exercise

Condition:   Chronic Pain
Intervention:   Behavioral: COMMENCE
Sponsor:   McMaster University
Completed - verified September 2016

Algovita Post-Market Clinical Study: Spinal Cord Stimulation to Treat Chronic Pain

Condition:   Chronic Pain
Intervention:   Device: Algovita Spinal Cord Stimulation system
Sponsor:   Nuvectra
Recruiting - verified May 2017

Patient Activation to Address Chronic Pain and Opioid Management in Primary Care

Condition:   Chronic Pain
Intervention:   Behavioral: Behavioral Based Treatment Model
Sponsors:   Kaiser Permanente;   Patient-Centered Outcomes Research Institute
Active, not recruiting - verified September 2016

Lidocaine Infusion for Chronic Pain in Opioid Dependent Patients

Condition:   Chronic Pain
Interventions:   Drug: Lidocaine infusion;   Drug: Saline infusion
Sponsor:   University of Texas Southwestern Medical Center
Recruiting - verified November 2016

Mind Body Syndrome (MBS) Therapy for the Treatment of Chronic Pain

Condition:   Chronic Pain
Intervention:   Behavioral: One-on-one interview and educational sessions. Reading material for educational series as below
Sponsor:   Beth Israel Deaconess Medical Center
Recruiting - verified March 2017

An Interventional Study to Compare the Efficacy and Tolerability With Targin® in Non-malignant Chronic Pain (GLORY)

Condition:   Chronic Pain
Intervention:   Drug: Oxycodone/naloxone
Sponsor:   Mundipharma Korea Ltd
Completed - verified January 2017

rTMS for the Treatment of Chronic Pain in GW1 Veterans

Condition:   Chronic Pain
Interventions:   Device: rTMS;   Device: Sham device
Sponsor:   VA Office of Research and Development
Terminated - verified April 2017

Web-based Cognitive-behavior Therapy (CBT) for Opioid-treated, Chronic Pain Patients With Aberrant Behavior

Condition:   Chronic Pain
Intervention:   Behavioral: Web-based CBT for chronic pain
Sponsors:   National Development and Research Institutes, Inc.;   National Institute on Drug Abuse (NIDA);   Beth Israel Medical Center
Completed - verified May 2017

Acupuncture and Chiropractic Care for Chronic Pain in an Integrated Health Plan

Condition:   Chronic Pain
Sponsors:   Kaiser Permanente;   University of Arizona;   Oregon Health and Science University
Completed - verified December 2016

Stanford Chronic Pain Self-Management Programme in Danish Chronic Pain Patients

Condition:   Chronic Pain
Intervention:   Behavioral: The Stanford Chronic Pain Self-Management Programme
Sponsors:   University of Aarhus;   TRYG Foundation;   Danish Committee for Health Education
Completed - verified June 2016

Telehealth Therapy for Chronic Pain: Comparison of In-person vs. Video-administered ACT for Pain

Condition:   Chronic Pain
Interventions:   Behavioral: In-Person ACT;   Behavioral: Telehealth ACT
Sponsor:   VA Office of Research and Development
Completed - verified June 2015

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2 thoughts on “Chronic Pain

  1. looking for long term study for relief low back pain with opioids, BEMA,R oxycotin or oxy IR in birmingham alabama. Need medication medicare will not pick up till Oct.2012. Been in pain management since 15 years ago. on disability now and no health insurance.REALLY NEED HELP WITH PAIN CONTROL.

    • Hi Deborah,
      I’m so sorry to hear about your pain situation, back pain is one of the most difficult things to manage. We can not recommend a particular trial for you, however, here is the process to follow to find a trial that you may be eligible for: 1)Fill out a clinical trial profile on JCT to help recruiters find you. 2) Type ‘back pain’ in the search box, choose your state, then choose ‘open studies’ and click submit to pull up the results. Several options should appear for the state of Alabama. I wish you the best of luck and hope that things get better.