Arthritis

About Arthritis Clinical Trials (Click to Open)

Join Clinical Trials for Arthritis

General Purpose:

Clinical Trials for ArthritisClinical trials for arthritis are typically dependent upon the type of arthritis. While there are over 100 different types, the most common include osteoarthritis, rheumatoid arthritis, and gout. Preventative clinical trials will evaluate the combined effects of interventional and educational preventative practices for older adults to improve risk factors for arthritis.

Living with arthritis means coping with the pain, so the aim of many clinical trials for all types of this disease will be to help you manage your pain. Some studies will do so by comparing different self-management programs, so that you will be informed as to the benefits of joining an arthritis education program.

Other pain management trials will assess the benefits of different medications, exercise, and other interventional measures. Rheumatoid arthritis studies may evaluate this disease’s affects on the body by comparing new and established RA patients, as well as the benefits of different medications on these resulting symptoms.

Given that basic functioning can become quite impaired in those suffering from arthritis, many studies will assess different interventional methods to help improve basic functioning. Some studies may test improved diagnostic measures in order to expedite proper treatment and pain management. These trials are ultimately determined to improve your quality of life.

What will Arthritis Clinical Trials be like?

Before starting a trial, your eligibility will be evaluated through clinical tests and medical history to ensure that you are the right fit for the aim of the trial. The goal of these trials is to improve your quality of life in some way, so inclusion criteria are intended to provide benefit and avoid wasting your time.

They are also put in place to avoid any risk, which could result if, for example, the trial were assessing a new pharmaceutical treatment that had detrimental interactions with another medication that you are taking.

To that end, you will be asked to give a detailed medical history and information from cancer screenings, blood pressure readings, immunizations, etc. You may also be asked to undergo cholesterol and glucose monitoring throughout the duration of the trial. In addition, you will need to provide details about any joint pain or stiffness that you are suffering from.

Typical Arthritis Clinical Trial Protocol:

If the main interventional mechanism being tested is behavioral, such as an exercise program, you will be assigned to an exercise group or given an exercise regimen to follow. You will then be asked to report on your symptoms so that potential benefit can be evaluated, and will also be given clinical tests including blood work for further assessment.

Functioning will also be assessed at various time points to measure impact. Trials seeking new and improved diagnostic measures will ask you to undergo these new methods, which may include magnetic resonance imaging (MRI) or ultrasonography.

Pharmaceutical clinical trials will provide different treatment groups varying doses to assess the treatment’s effectiveness. In all arthritis clinical trials, you will be evaluated throughout the duration of the trial to ensure that nothing goes awry.

You should also note that as with any clinical trial, it is possible that you will be randomly selected for the placebo group. You would therefore undergo the same procedures as the treatment group without receiving the actual treatment being tested.

If you have any concerns regarding the treatment that you are receiving in the trial, inform your trial contact immediately. The ultimate goal of these trials is to benefit those with arthritis, so those involved with the trial are there to help you.

Current Search Term: “Arthritis”

 

Additional Suggested Search Terms

Arthritis Exercise Program, Pain Management in Arthritis, Osteoarthritis, Coping Skills and Rheumatoid Arthritis, Healthy Aging and Arthritis Prevention



Mesenchymal Stem Cells in Early Rheumatoid Arthritis


Condition:   Rheumatoid Arthritis
Interventions:   Biological: 2 million hMSC/kg;   Biological: 4 million hMSC/kg;   Biological: 6 million hMSC/kg;   Biological: placebo
Sponsors:   MetroHealth Medical Center;   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Not yet recruiting


NEUROIMPA - Intraarticular Application of Opioids in Chronic Arthritis of the Knee Joint


Condition:   Knee Arthritis
Interventions:   Drug: Morphine Sulfate;   Drug: Triamcinolone;   Drug: placebo
Sponsors:   Hildrun Haibel;   DLR German Aerospace Center
Recruiting


REMission INDuction in Very Early Rheumatoid Arthritis


Condition:   Arthritis, Rheumatoid
Intervention:   Other: Taper
Sponsor:   UMC Utrecht
Recruiting


Rheumatoid Arthritis Patients and Porphyromonas Gingivalis


Condition:   Rheumatoid Arthritis
Interventions:   Procedure: blood sample;   Procedure: synovial tissue
Sponsor:   Centre Hospitalier Universitaire de Saint Etienne
Recruiting


A Study of Subjects With Psoriatic Arthritis to Investigate the Effectiveness of Adalimumab Introduction Compared With Methotrexate Dose Escalation


Condition:   Psoriatic Arthritis
Interventions:   Biological: adalimumab;   Drug: methotrexate (MTX)
Sponsor:   AbbVie
Recruiting


Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of VAY736 in Rheumatoid Arthritis Patients


Condition:   Rheumatoid Arthritis
Interventions:   Biological: VAY736;   Biological: VAY736 placebo
Sponsor:   Novartis Pharmaceuticals
Active, not recruiting


Special Investigation in Patients With Psoriatic Arthritis (PsA) (Working Productivity and Activity Impairment (WPAI))


Condition:   Psoriatic Arthritis
Intervention:  
Sponsor:   AbbVie
Completed


CPMC Early Undifferentiated Arthritis Registry


Condition:   Arthritis
Intervention:  
Sponsor:   California Pacific Medical Center Research Institute
Recruiting


Pro-calcitonin for Early Detection of Septic Arthritis


Condition:   Arthritis, Infectious
Intervention:  
Sponsor:   Children's Hospitals and Clinics of Minnesota
Active, not recruiting


The PRESS RA: Protein and Resistance Exercise Supplementation Study for Rheumatoid Arthritis


Condition:   Rheumatoid Arthritis
Interventions:   Dietary Supplement: Protein;   Dietary Supplement: Carbohydrate (Placebo);   Other: Resistance Exercise Program
Sponsors:   Johns Hopkins University;   National Institute on Aging (NIA);   American College of Rheumatology Research and Education Foundation
Suspended


Discovering the Antecedents of Rheumatoid Arthritis Flare


Condition:   Rheumatoid Arthritis
Intervention:  
Sponsor:   Rockefeller University
Recruiting


Safety and Efficacy Study of Apremilast to Treat Psoriatic Arthritis


Condition:   Psoriatic Arthritis
Interventions:   Drug: Apremilast 30 mg;   Drug: Placebo
Sponsor:   Celgene
Completed


Extension Study up to 3 Years for Secukinumab in Psoriatic Arthritis


Condition:   Psoriatic Arthritis
Intervention:   Drug: Secukinumab
Sponsor:   Novartis Pharmaceuticals
Active, not recruiting


Investigation of the Safety and Efficacy of Iguratimod in Patients With Rheumatoid Arthritis


Condition:   Rheumatoid Arthritis
Intervention:   Drug: Iguratimod
Sponsor:   Eisai Co., Ltd.
Completed



Effect of Monoclonal Anti-IL6 Antibody (Tocilizumab) on the Cardiovascular Risk in Patients With Rheumatoid Arthritis


Condition:   Rheumatoid Arthritis
Intervention:   Other: Braquial ecography
Sponsors:   Hospital Universitario de Canarias;   Roche Pharma AG
Active, not recruiting


Special Investigation in Patients With Rheumatoid Arthritis (Combo Study; Adalimumab With High Dose Methotrexate)


Condition:   Rheumatoid Arthritis
Intervention:  
Sponsor:   AbbVie (prior sponsor, Abbott)
Active, not recruiting


A Nutrition Intervention for Arthritis -2


Condition:   Rheumatoid Arthritis
Interventions:   Other: Plant-based diet;   Other: Supplement
Sponsor:   Physicians Committee for Responsible Medicine
Active, not recruiting


Yoga as Self-Care for Arthritis in Minority Communities


Conditions:   Rheumatoid Arthritis;   Arthritis
Intervention:   Behavioral: Yoga
Sponsor:   National Institutes of Health Clinical Center (CC)
Completed


Canadian Humira Post Marketing Observational Epidemiological Study Assessing Effectiveness in Psoriatic Arthritis


Condition:   Psoriatic Arthritis
Intervention:  
Sponsors:   AbbVie (prior sponsor, Abbott);   JSS Medical Research Inc.;   Cato Research
Recruiting


Special Investigation in Patients With Rheumatoid Arthritis (Working Productivity Activity Impairment)


Condition:   Rheumatoid Arthritis
Intervention:  
Sponsor:   AbbVie (prior sponsor, Abbott)
Completed


Study of Apremilast to Evaluate the Safety and Effectiveness for Patients With Rheumatoid Arthritis


Condition:   Rheumatoid Arthritis
Interventions:   Drug: Apremilast 30 mg;   Drug: Apremilast 20 mg;   Drug: Placebo
Sponsor:   Celgene
Terminated


Sleep and Immunity in Rheumatoid Arthritis : Remicade Substudy


Condition:   Rheumatoid Arthritis
Intervention:   Drug: Remicade
Sponsors:   University of California, Los Angeles;   National Heart, Lung, and Blood Institute (NHLBI)
Completed


Laser-based Photoacoustic Tomography of Human Inflammatory Arthritis


Condition:   Arthritis, Rheumatoid
Interventions:   Procedure: Laser Based Photoacoustic Tomography, MRI, Ultrasound;   Procedure: laser based photoacoustic tomography, MRI, ultrasound
Sponsor:   University of Michigan
Recruiting


Lovastatin for the Treatment of Mildly Active Rheumatoid Arthritis


Condition:   Rheumatoid Arthritis
Interventions:   Drug: Lovastatin;   Drug: Placebo
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   Autoimmunity Centers of Excellence
Completed

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