Anemia

About Anemia Clinical Trials (Click to Open)

Join Clinical Trials for Clinical Trials for Anemia

Clinical Trials for AnemiaIn clinical trials for anemia, medications will be tested that should ideally help treat the different forms of anemia, as well as improve the quality of life of those afflicted with this disease.

They will also test blood and marrow stem cell transplants for those with severe forms, the effectiveness of bone marrow treatments for children with sickle cell disease, medication to improve blood counts for those with aplastic anemia, and gene therapy for those with Fanconi anemia.

What is a typical trial like?

Potential study participants will undergo blood tests to determine eligibility. Tests such as blood counts assessments will be administered for comparison purposes with future tests to determine the success rate of treatments. Certain trials will also require evidence of a family history with inherited forms of anemia in order for you to be eligible.

Typical Trial Protocol:

Participants may receive some form of medication intravenously for a specified time course, during which they may be continuously monitored in the associated research hospital with the intention of studying drug initiation.

In FDA approved drug trials, participants may take the approved prescription pill for the recommended duration and be monitored while on the medication. They will also be required to attend follow-ups for a specified time after stopping the medication.

Those with severe forms of inherited anemia may be eligible to join a clinical trial in which they will undergo stem cell transplant and post transplant therapy to reduce the risk of host versus graft disease. Assistance will be provided for the cost of living away from home during the course of the procedure and post-procedural therapy.

You should also note that as with any clinical trial, it is possible that you will be randomly selected for the placebo group. You would therefore undergo the same procedures as the treatment group without receiving the actual treatment being tested.

Suggested Search Terms:

Aplastic Anemia, Sickle Cell Anemia, Diamond Blackfan Anemia, Gene therapy and Fanconi Anemia, Stem Cell Transplants for Anemia 



The Burden of Childhood Anemia in Bangladesh: Does Socioeconomic Status Matter?


Condition:   Anemia
Intervention:   Diagnostic Test: Anemia
Sponsor:   Shahjalal University of Science and Technology
Completed - verified April 2017


Burden of Anemia Among Ever-married Women in Bangladesh: Does Household Economic Inequality Matter?


Condition:   Anemia
Intervention:  
Sponsor:   Shahjalal University of Science and Technology
Completed - verified April 2017


Iron Sucrose Versus Ferrous Bis-glycinate for Treatment of Iron Deficiency Anemia


Condition:   Anemia
Interventions:   Drug: Iron Sucrose Injection;   Drug: Ferrous Bisglycinate
Sponsor:   Assiut University
Recruiting - verified April 2017


Study of Romiplostim(AMG531) in Subjects With Aplastic Anemia


Condition:   Aplastic Anemia
Intervention:   Biological: Romiplostim
Sponsor:   Kyowa Hakko Kirin Co., Ltd
Active, not recruiting - verified May 2017


Use of Cast Iron Pots to Improve Maternal Anemia


Condition:   Iron-deficiency Anemia
Interventions:   Device: Cast Iron Pot;   Device: Alumnium Pot
Sponsor:   Weill Medical College of Cornell University
Recruiting - verified February 2017


Study of Beet Juice for Patients With Sickle Cell Anemia


Condition:   Sickle Cell Anemia
Intervention:   Drug: beet juice (Unbeetable)
Sponsors:   Daniel Kim-Shapiro;   Wake Forest University;   National Heart, Lung, and Blood Institute (NHLBI)
Suspended - verified March 2017


Ferinject® Assessment In GastRectomy Patients With Acute Isovolemic Anemia (FAIRY)


Condition:   Anemia
Interventions:   Drug: Ferinject®;   Drug: normal saline
Sponsor:   National Cancer Center, Korea
Completed - verified December 2016


Preoperative Intravenous Iron to Treat Anaemia in Major Surgery


Condition:   Anaemia
Interventions:   Drug: Ferric carboxymaltose;   Drug: Normal saline
Sponsor:   University College, London
Recruiting - verified April 2015


Quercetin in Children With Fanconi Anemia; a Pilot Study


Condition:   Fanconi Anemia
Intervention:   Drug: Quercetin (dietary supplement)
Sponsor:   Children's Hospital Medical Center, Cincinnati
Recruiting - verified August 2016


Effects of Vitamin D and Marine Omega-3 Fatty Acids on Anemia


Condition:   Anemia
Interventions:   Dietary Supplement: Vitamin D3 .;   Drug: omega-3 fatty acids (fish oil);   Dietary Supplement: Vitamin D3 placebo;   Dietary Supplement: Fish oil placebo
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI);   Office of Dietary Supplements (ODS);   National Center for Complementary and Integrative Health (NCCIH)
Enrolling by invitation - verified February 2017


Mechanisms Accounting for Unexplained Anemia in the Elderly


Condition:   Anemia
Intervention:   Procedure: Biotin RBC survival
Sponsor:   National Institute on Aging (NIA)
Completed - verified July 8, 2016


Trial To Evaluate the Efficacy of Oral Salsalate in the Treatment of Older Adults With Unexplained Anemia


Condition:   Anemia
Interventions:   Drug: Salsalate;   Drug: Placebo
Sponsors:   Harvey Jay Cohen;   National Institute on Aging (NIA)
Terminated - verified August 2016


Multicenter Transplant Study for Fanconi Anemia


Condition:   Fanconi Anemia
Interventions:   Drug: Chemotherapy;   Biological: Miltenyi CliniMACS
Sponsor:   Children's Hospital Medical Center, Cincinnati
Completed - verified June 2016


Study to Assess the Efficacy and Safety of HX575 in the Treatment of Chemotherapy Associated Anemia in Cancer Patients


Condition:   Anemia
Interventions:   Drug: HX575, solution for injection (s.c.);   Drug: ERYPO®, Janssen-Cilag, solution for injection (s.c.)
Sponsors:   Sandoz;   Hexal AG
Completed - verified October 2016


Safety and Tolerability of Ferric Carboxymaltose (FCM) Versus Iron Dextran in Treating Iron Deficiency Anemia


Condition:   Anemia
Interventions:   Drug: Ferric Carboxymaltose;   Drug: Iron Dextran
Sponsor:   Luitpold Pharmaceuticals
Completed - verified November 2016


Safety and Tolerability of a Single Dose of FCM vs. Standard of Care in Treating Iron Deficiency Anemia


Condition:   Anemia
Interventions:   Drug: Ferric Carboxymaltose;   Drug: Standard Medical Care (SMC)
Sponsor:   Luitpold Pharmaceuticals
Completed - verified March 2017


Study to Evaluate the Efficacy and Safety of HX 575 vs ERYPO® for the Treatment of Anemia in Hemodialysis Patients


Condition:   Anemia
Interventions:   Drug: HX575 Solution for i.v. injection;   Drug: ERYPO®, Janssen-Cilag, Germany
Sponsors:   Sandoz;   Hexal AG
Completed - verified October 2016


Cytoxan, Fludara, and Antithymocyte Globulin Conditioning Followed By Stem Cell Transplant in Treating Fanconi Anemia


Condition:   Fanconi Anemia
Interventions:   Biological: Anti-Thymocyte Globulin;   Drug: Cyclophosphamide;   Drug: Fludarabine;   Procedure: Hematopoietic Stem Cell Transplantation;   Drug: Methylprednisolone;   Drug: Filgrastim;   Drug: Cyclosporine;   Drug: Mycophenolate Mofetil
Sponsor:   Masonic Cancer Center, University of Minnesota
Recruiting - verified March 2017


Allogeneic Stem Cell Transplantation for Patients With Severe Aplastic Anemia


Condition:   Anemia, Aplastic
Intervention:   Drug: Cyclophosphamide,Campath IH and TBI
Sponsor:   Mayo Clinic
Completed - verified March 2017


Effectiveness of Arginine as a Treatment for Sickle Cell Anemia


Condition:   Anemia, Sickle Cell
Interventions:   Drug: Arginine;   Drug: Placebo
Sponsors:   Children's Hospital & Research Center Oakland;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified June 2009


Fludarabine-based Conditioning for Severe Aplastic Anemia (BMT CTN 0301)


Condition:   Anemia, Aplastic
Interventions:   Drug: Fludarabine;   Drug: Cyclophosphamide 150mg;   Drug: Cyclophosphamide 100mg;   Drug: Cyclophosphamide 50mg
Sponsors:   Medical College of Wisconsin;   National Heart, Lung, and Blood Institute (NHLBI);   Blood and Marrow Transplant Clinical Trials Network;   National Cancer Institute (NCI);   National Marrow Donor Program
Completed - verified August 2016


Hematopoietic Stem Cell Transplantation in High Risk Patients With Fanconi Anemia


Condition:   Fanconi Anemia
Interventions:   Biological: anti-thymocyte globulin;   Biological: filgrastim;   Drug: busulfan;   Drug: cyclophosphamide;   Drug: fludarabine phosphate;   Drug: methylprednisolone;   Biological: Hematopoietic stem cell transplantation
Sponsor:   Masonic Cancer Center, University of Minnesota
Recruiting - verified February 2017


Prevention of Severe Anaemia in Gambian Children


Condition:   Anemia
Intervention:   Drug: sulfadoxine-pyrimethamine
Sponsors:   London School of Hygiene and Tropical Medicine;   Department of State for Health and Social Welfare, The Gambia
Completed - verified January 2017


Trial of Oral Glutamine in Patients With Sickle Cell Anemia


Condition:   Anemia, Sickle Cell
Interventions:   Drug: Glutamine;   Drug: Placebo
Sponsors:   St. Jude Children's Research Hospital;   Thrasher Research Fund
Terminated - verified March 2010


Hydroxyurea for the Treatment of Patients With Sickle Cell Anemia


Condition:   Sickle Cell Anemia
Intervention:   Drug: Hydroxyurea
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified May 18, 2015

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