Mouth (Oral) Cancer



The Optimal Neck Treatments Strategy of Early Oral Cancer Based on Adverse Pathological Factor


Condition:   Oral Cancer
Interventions:   Radiation: Radiotherapy;   Procedure: Elective neck dissection
Sponsor:   Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Recruiting - verified January 2017


Effect of FDG-PET/CT for Simulation and Radiation Treatment Planning in Oral Cancer Patients


Conditions:   Oral Cancer;   Radiotherapy; Complications
Intervention:   Device: PET/CT
Sponsor:   Zhongnan Hospital
Not yet recruiting - verified December 2016


Participatory Research for Fine-tuning of a 2.0 System to Optimise Home Management of Oral Cancer Therapies.


Conditions:   Cancer;   Oral Drug Administration
Intervention:   Device: TreC-Onco
Sponsors:   Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori;   Kessler Foundation
Recruiting - verified September 2016


Validation of DNA Methylation Biomarkers for Oral Cancer Detection-Follow up Study


Condition:   Oral Cancer
Intervention:  
Sponsor:   National Taiwan University Hospital
Recruiting - verified September 2016


Non Invasive Oral Cancer Screening Among HIV Infected Individuals


Conditions:   Malignant Neoplasms of Mesothelial and Soft Tissue;   Human Immunodeficiency Virus
Interventions:   Behavioral: Screening Interview;   Device: Carbon Monoxide Test;   Behavioral: Self-Help Materials;   Procedure: Visual Oral Screening Examination;   Procedure: Direct Fluorescent Oral Visualization Examination;   Procedure: Oral Biopsy
Sponsors:   M.D. Anderson Cancer Center;   Baylor College of Medicine;   The University of Texas Health Science Center, Houston
Recruiting - verified January 2017


Cytological Screening for Early Diagnosis of Precancerous or Cancerous Lesions of Oral Cavity


Condition:   Mouth Neoplasms
Intervention:   Device: Orcellex® Rovers brush
Sponsor:   University Hospital, Toulouse
Recruiting - verified March 2017


Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology


Conditions:   Head and Neck Cancer;   Squamous Cell Carcinoma (SCC) of the Oral Cavity
Intervention:   Device: Reflectance Confocal Microscopy
Sponsor:   Memorial Sloan Kettering Cancer Center
Recruiting - verified January 2017


Sentinel Lymph Node Mapping of Oral Cancer Using Near-Infrared Fluorescence Imaging


Condition:   Head and Neck Neoplasms
Interventions:   Procedure: Sentinel lymph node mapping;   Drug: Indocyanine Green (ICG);   Device: near-infrared fluorescence (NIR) imaging (Pinpoint, Novadaq, Waterloo)
Sponsor:   University Health Network, Toronto
Recruiting - verified October 2016


Establishing Lymphedema and Fibrosis Measures in Oral Cancer Patients


Conditions:   Oral Cavity Cancer;   Oropharyngeal Cancer;   Lymphedema;   Fibrosis
Interventions:   Other: LEF measures;   Procedure: Technical measure;   Procedure: Technical measure
Sponsors:   Vanderbilt-Ingram Cancer Center;   National Cancer Institute (NCI);   National Institute of Dental and Craniofacial Research (NIDCR)
Recruiting - verified January 2017


Oral State of Patients Affected by an Oral Cancer Before and After Radiotherapy - 3-years Prospective Study


Condition:   Oral Cancer
Intervention:   Behavioral: Quality of life survey/ dental statement
Sponsor:   Assistance Publique Hopitaux De Marseille
Recruiting - verified August 2016


Salivary and Serum Levels of Chemerin and MMP-9 in Oral Premalignant and Malignant Lesions


Conditions:   Precancerous Conditions;   Oral Cancer
Intervention:  
Sponsor:   Cairo University
Completed - verified February 2017


Diagnostic Aids for Detection and Diagnosis of Oral Cancer


Condition:   Head and Neck Cancer
Interventions:   Behavioral: Questionnaire;   Device: POS + PS2 + VELscope;   Procedure: Oral Brush Biopsy
Sponsors:   M.D. Anderson Cancer Center;   National Institutes of Health (NIH);   William Marsh Rice University
Withdrawn - verified April 2017


Improving Adherence to Oral Cancer Agents and Self Care of Symptoms Using an IVR


Conditions:   Prostatic Neoplasms;   Breast Neoplasms;   Colorectal Neoplasms;   Melanoma;   Leukemia
Intervention:   Behavioral: Interactive Voice Response (IVR) Reminders
Sponsors:   Michigan State University;   National Cancer Institute (NCI)
Completed - verified September 2016


Analysis Of Sensory Recovery Of Donor Size And Quality Life In Oral Cancer Patients


Condition:   Oral Cancer
Intervention:  
Sponsor:   Kaohsiung Medical University Chung-Ho Memorial Hospital
Completed - verified July 2013


Assessment of Mandibular Bone Invasion With MRI Using SWIFT


Condition:   Oral Cancer
Intervention:  
Sponsor:   University of Minnesota - Clinical and Translational Science Institute
Enrolling by invitation - verified October 2016


Autofluorescence Detection of Oral Malignancies and Database and Biospecimen Collection to Identify Biomarkers of Head and Neck Tumor Progression


Condition:   Oral Cancer
Intervention:  
Sponsor:   Roswell Park Cancer Institute
Active, not recruiting - verified March 2017


Freeze-Dried Black Raspberries in Preventing Oral Cancer Recurrence in High-Risk Appalachian Patients Previously Treated With Surgery For Oral Cancer


Conditions:   Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity;   Stage I Squamous Cell Carcinoma of the Oropharynx;   Stage I Verrucous Carcinoma of the Oral Cavity;   Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity;   Stage II Squamous Cell Carcinoma of the Oropharynx;   Stage II Verrucous Carcinoma of the Oral Cavity;   Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity;   Stage III Squamous Cell Carcinoma of the Oropharynx;   Stage III Verrucous Carcinoma of the Oral Cavity;   Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity;   Stage IVA Squamous Cell Carcinoma of the Oropharynx;   Stage IVA Verrucous Carcinoma of the Oral Cavity;   Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity;   Stage IVB Squamous Cell Carcinoma of the Oropharynx;   Stage IVB Verrucous Carcinoma of the Oral Cavity;   Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity;   Stage IVC Squamous Cell Carcinoma of the Oropharynx;   Stage IVC Verrucous Carcinoma of the Oral Cavity;   Tongue Cancer
Interventions:   Drug: lyophilized black raspberry lozenge;   Other: survey administration;   Other: laboratory biomarker analysis;   Other: pharmacological study
Sponsor:   Ohio State University Comprehensive Cancer Center
Active, not recruiting - verified January 2017


Phase 1b Food Based Modulation of Biomarkers in Human Tissues at High-Risk for Oral Cancer.


Conditions:   Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma;   Salivary Gland Squamous Cell Carcinoma;   Stage 0 Hypopharyngeal Cancer;   Stage 0 Laryngeal Cancer;   Stage 0 Lip and Oral Cavity Cancer;   Stage 0 Nasopharyngeal Cancer;   Stage 0 Oropharyngeal Cancer;   Stage 0 Paranasal Sinus and Nasal Cavity Cancer;   Stage I Salivary Gland Cancer;   Stage I Squamous Cell Carcinoma of the Hypopharynx;   Stage I Squamous Cell Carcinoma of the Larynx;   Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity;   Stage I Squamous Cell Carcinoma of the Nasopharynx;   Stage I Squamous Cell Carcinoma of the Oropharynx;   Stage I Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity;   Stage I Verrucous Carcinoma of the Larynx;   Stage I Verrucous Carcinoma of the Oral Cavity;   Stage II Salivary Gland Cancer;   Stage II Squamous Cell Carcinoma of the Hypopharynx;   Stage II Squamous Cell Carcinoma of the Larynx;   Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity;   Stage II Squamous Cell Carcinoma of the Nasopharynx;   Stage II Squamous Cell Carcinoma of the Oropharynx;   Stage II Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity;   Stage II Verrucous Carcinoma of the Larynx;   Stage II Verrucous Carcinoma of the Oral Cavity;   Stage III Salivary Gland Cancer;   Stage III Squamous Cell Carcinoma of the Hypopharynx;   Stage III Squamous Cell Carcinoma of the Larynx;   Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity;   Stage III Squamous Cell Carcinoma of the Nasopharynx;   Stage III Squamous Cell Carcinoma of the Oropharynx;   Stage III Verrucous Carcinoma of the Larynx;   Stage III Verrucous Carcinoma of the Oral Cavity;   Stage IV Squamous Cell Carcinoma of the Hypopharynx;   Stage IV Squamous Cell Carcinoma of the Nasopharynx;   Stage IVA Salivary Gland Cancer;   Stage IVA Squamous Cell Carcinoma of the Larynx;   Stage IVA Oral Cavity Squamous Cell Carcinoma;   Stage IVA Squamous Cell Carcinoma of the Oropharynx;   Stage IVA Nasal Cavity and Paranasal Sinus Cancer;   Stage IVA Verrucous Carcinoma of the Larynx;   Stage IVA Verrucous Carcinoma of the Oral Cavity;   Stage IVB Salivary Gland Cancer;   Stage IVB Squamous Cell Carcinoma of the Larynx;   Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity;   Stage IVB Squamous Cell Carcinoma of the Oropharynx;   Stage IVB Oral Cavity Squamous Cell Carcinoma;   Stage IVB Verrucous Carcinoma of the Larynx;   Stage IVB Verrucous Carcinoma of the Oral Cavity;   Stage IVC Salivary Gland Cancer;   Stage IVC Squamous Cell Carcinoma of the Larynx;   Stage IVC Oral Cavity Squamous Cell Carcinoma;   Stage IVC Squamous Cell Carcinoma of the Oropharynx;   Paranasal Sinus and Nasal Cavity Squamous Cell Carcinoma;   Stage IVC Verrucous Carcinoma of the Larynx;   Stage IVC Verrucous Carcinoma of the Oral Cavity;   Tongue Cancer
Interventions:   Other: placebo;   Other: laboratory biomarker analysis;   Other: questionnaire administration;   Drug: chemoprevention;   Drug: chemoprevention;   Other: placebo
Sponsor:   Ohio State University Comprehensive Cancer Center
Active, not recruiting - verified January 2017


Polarized Reflectance Spectroscopy for Oral Lesions


Condition:   Oral Cancer
Intervention:   Device: Polarized Reflectance Spectroscopy System
Sponsors:   British Columbia Cancer Agency;   M.D. Anderson Cancer Center;   University of Texas at Austin
Completed - verified January 2017


Vitamin D Plus Celecoxib Therapy to Stimulate Intratumoral Immune Reactivity


Condition:   Mouth Neoplasms
Interventions:   Drug: Celecoxib;   Drug: Calcitriol;   Drug: Celecoxib plus Calcitriol
Sponsor:   VA Office of Research and Development
Completed - verified January 2017


Fluorescence & Reflectance Imaging to Detect Oral Neoplasia


Condition:   Oral Cancer
Interventions:   Procedure: Portable Spectroscopy System;   Procedure: Multispectral Digital Microscope;   Procedure: Fast Excitation-Emission Matrix System
Sponsors:   M.D. Anderson Cancer Center;   National Institute of Dental and Craniofacial Research (NIDCR)
Recruiting - verified August 2016


Spectroscopy for Diagnostic Assessment of Oral Mucosal Lesions


Condition:   Oral Cancer
Intervention:   Procedure: Fluorescence Spectroscopy
Sponsor:   M.D. Anderson Cancer Center
Recruiting - verified January 2017


Oral Margin Spectroscopy Detection Using Optical Spectroscopy


Condition:   Oral Tumors
Interventions:   Device: FastEEM4 System;   Device: Multispectral Digital Microscope
Sponsors:   M.D. Anderson Cancer Center;   National Institute of Dental and Craniofacial Research (NIDCR);   National Institutes of Health (NIH)
Active, not recruiting - verified March 2017


Erlotinib Prevention of Oral Cancer (EPOC)


Condition:   Oral Cancer
Interventions:   Drug: Erlotinib;   Drug: Placebo
Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI);   Astellas Pharma US, Inc.
Active, not recruiting - verified September 2016


Biomarkers for Oral Cancer


Conditions:   Lichen Planus;   Oral Leukoplakia
Intervention:  
Sponsors:   National Institute of Dental and Craniofacial Research (NIDCR);   National Cancer Institute (NCI)
Completed - verified June 10, 2016

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