Multiple Sclerosis

Join Clinical Trials for Multiple Sclerosis

Join Clinical Trials for Multiple Sclerosis

General purpose: 
Research related to multiple sclerosis may investigate new drugs in an effort to find more effective treatments for the disease, whereas other studies may investigate how multiple sclerosis develops.

That research can lead to additional research into ways of preventing the development of multiple sclerosis altogether. In addition, research may also focus on the role of the immune system in the development of multiple sclerosis, as well as the impact that genetics has in increasing the risk of multiple sclerosis.

Multiple Sclerosis Clinical Trials Continued … (Click to Open)

Join Clinical Trials for Multiple Sclerosis

Multiple Sclerosis Clinical Trials

What do clinical trials for Multiple Sclerosis involve?

Clinical trials will vary widely in the information they collect, as well as the tests and procedures they use. All of these factors will depend on individual study designs, which will differ greatly between trials. However, below is a list of common procedures and data that are frequently collected during a trial for multiple sclerosis:

  • Blood tests to monitor safety and effectiveness of new drug treatments for multiple sclerosis.
  • Imaging studies, in particular MRI, to monitor the effects of new drugs therapies and other treatments.
  • Blood tests to evaluate specific genetic characteristics or antibodies.
  • Neurological exams
  • Eye exams

Examples of Multiple Sclerosis- related research topics:

  • Studies comparing a conventional treatment for multiple sclerosis with a newly developed drug to determine which is most effective.
  • Studies that use MRI to observe how multiple sclerosis lesions change in size and number within the brain and spinal cord in relation to specific treatments.
  • Studies of blood and tissue samples from large numbers of multiple sclerosis patients in order to observe any common genetic mutations.
  • The effects of pregnancy on women with multiple sclerosis.

Suggested search terms for Multiple Sclerosis:

“Multiple Sclerosis”  “multiple sclerosis treatment,” “multiple sclerosis progression,” “multiple sclerosis diet,” “multiple sclerosis fatigue,” and “multiple sclerosis vitamin D.”



Comparison of Two Community Based Exercise Protocols in People With Multiple Sclerosis


Condition:   Multiple Sclerosis
Intervention:   Other: Personal training exercises
Sponsor:   Texas Woman's University
Recruiting


Efficacy of tDCS on Pain in Multiple Sclerosis


Condition:   Multiple Sclerosis
Interventions:   Device: Real-tDCS + rehabilitation programme;   Device: Sham-tDCS + rehabilitation programme
Sponsor:   University Hospital of Ferrara
Recruiting


Multiple Sclerosis Registry in Argentina (RelevarEM)


Condition:   Multiple Sclerosis
Intervention:   Other: Natural history of disease
Sponsor:   Hospital Italiano de Buenos Aires
Not yet recruiting


Evaluation of the Onset of Action in Highly Active Multiple Sclerosis (MS)


Condition:   Multiple Sclerosis
Intervention:   Drug: Mavenclad®
Sponsor:   Merck KGaA
Not yet recruiting


Effects of Inspiratory Muscle Training in Persons With Advanced Multiple Sclerosis


Condition:   Multiple Sclerosis
Intervention:   Other: Inspiratory Muscle Trainer (IMT)
Sponsors:   University of Michigan;   National Multiple Sclerosis Society
Recruiting


Fingolimod Versus Dimethyl-fumarate in Multiple Sclerosis


Condition:   Relapsing Remitting Multiple Sclerosis
Interventions:   Drug: Fingolimod;   Drug: Dimethyl Fumarate
Sponsors:   Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta;   Patient-Centered Outcomes Research Institute;   Universita degli Studi di Genova
Recruiting


Early Exercise Efforts in Multiple Sclerosis


Condition:   Multiple Sclerosis
Interventions:   Combination Product: Systematic exercise training;   Behavioral: Educational program
Sponsors:   University of Aarhus;   University of Southern Denmark;   Region of Southern Denmark
Recruiting


Efficacy and Safety of Ofatumumab Compared to Placebo in Patients With Relapsing Multiple Sclerosis Followed by Extended Treatment With Open-label Ofatumumab


Condition:   Relapsing Multiple Sclerosis
Interventions:   Drug: Ofatumumab subcutaneous injection;   Drug: Placebo subcutaneous injection matching ofatumumab
Sponsor:   Novartis Pharmaceuticals
Recruiting


Obstetric Anesthesia and Analgesia and Multiple Sclerosis


Condition:   Multiple Sclerosis
Intervention:   Other: Data search
Sponsors:   Brno University Hospital;   Faculty of medicine, Masaryk University Brno
Completed


Physical Telerehabilitation in Multiple Sclerosis


Condition:   Multiple Sclerosis
Interventions:   Other: Home telerehabilitation;   Other: Usual Care
Sponsors:   Columbia University;   United States Department of Defense
Recruiting


Medication Usage and Patient Reported Outcomes Evaluation Via myBETAapp in Patients With Multiple Sclerosis Treated With Betaferon: a Pilot Study


Condition:   Multiple Sclerosis
Interventions:   Drug: Interferon beta-1b (Betaferon, BAY86-5046);   Device: Betaconnect auto-injector;   Device: myBETAapp
Sponsor:   Bayer
Recruiting


Reduced-intensity Immunoablation and Autologous Hematopoietic Stem Cell Transplantation (AHSCT) for Multiple Sclerosis


Condition:   Multiple Sclerosis
Interventions:   Biological: Autologous Hematopoietic Stem Cell;   Drug: BEAM Regimen
Sponsor:   Makati Medical Center
Recruiting


A Multicenter Observational Study to Evaluate Pediatric Multiple Sclerosis in Brazil


Condition:   Multiple Sclerosis
Interventions:   Diagnostic Test: anti-aquaporin-4 antibody;   Diagnostic Test: anti-myelin oligodendrocyte glycoprotein
Sponsors:   Pontificia Universidade Católica do Rio Grande do Sul;   TEVA
Recruiting


Pilot Diet Study for Multiple Sclerosis


Condition:   Multiple Sclerosis
Interventions:   Behavioral: Dietary Intervention;   Behavioral: Non-dietary Intervention Arm
Sponsor:   Icahn School of Medicine at Mount Sinai
Active, not recruiting


Swiss Multiple Sclerosis Registry


Condition:   Multiple Sclerosis
Intervention:  
Sponsors:   Swiss Multiple Sclerosis Registry;   University of Zurich, Epidemiology, Biostatistics and Prevention Institute;   Schweizerische Multiple Sklerose Gesellschaft
Recruiting


A Reeducation Program to Effort to Improve the Walking of Multiple Sclerosis Patients


Condition:   Multiple Sclerosis
Intervention:   Other: Effort reeducation program
Sponsor:   Lille Catholic University
Not yet recruiting


Phase 2 Study of Ublituximab in Patients With Relapsing Forms of Multiple Sclerosis


Condition:   Multiple Sclerosis
Interventions:   Biological: Ublituximab;   Drug: Placebo
Sponsor:   TG Therapeutics, Inc.
Active, not recruiting


Pathological Basis of MRI Signal Changes in Multiple Sclerosis


Condition:   Multiple Sclerosis
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting


A Study to Evaluate the Safety of Long Term Treatment With Teriflunomide 14 mg Once Daily in Patients With a First Clinical Episode Suggestive of Multiple Sclerosis in a Long-term Extension Period


Condition:   Multiple Sclerosis
Intervention:   Drug: Teriflunomide
Sponsor:   Centre Hospitalier Universitaire de Nice
Active, not recruiting


Oral Ponesimod Versus Teriflunomide In Relapsing MUltiple Sclerosis


Condition:   Multiple Sclerosis
Interventions:   Drug: ponesimod;   Drug: teriflunomide
Sponsor:   Actelion
Active, not recruiting


Cognitive Evolution in Tysabri Treated Multiple Sclerosis Patients - A Three Year Extension


Condition:   Multiple Sclerosis
Intervention:   Other: Observational Cognitive assessments
Sponsors:   Clinique Neuro-Outaouais;   CogState Ltd.
Completed


Physical Telerehabilitation in Veterans With Multiple Sclerosis


Condition:   Multiple Sclerosis
Intervention:   Device: Multiple Sclerosis Home Automated Telemanagement (MS HAT) system
Sponsors:   University of Maryland;   Baltimore VA Medical Center
Completed


Integrative Group-based Cognitive Rehabilitation Efficacy in Multiple Sclerosis


Condition:   Multiple Sclerosis
Intervention:   Other: cognitive remediation program: REHACOP
Sponsor:   University of Deusto
Completed


Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis


Condition:   Multiple Sclerosis
Interventions:   Drug: Interferon beta-1a i.m. injections;   Drug: Fingolimod oral capsules;   Drug: Placebo oral capsule;   Drug: Placebo i.m. injection
Sponsor:   Novartis Pharmaceuticals
Active, not recruiting


Evaluation of Autologous Mesenchymal Stem Cell Transplantation (Effects and Side Effects) in Multiple Sclerosis


Condition:   Multiple Sclerosis
Interventions:   Biological: intravenous injection of mesenchymal stem cells;   Biological: injection of cell free media
Sponsor:   Royan Institute
Completed

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