Cannabis Addiction (Marijuana)



E-cigarette THC Study


Condition:   Marijuana Dependence
Intervention:   Drug: Tetrahydrocannabinol
Sponsors:   University of California, San Francisco;   National Institutes of Health (NIH)
Not yet recruiting - verified November 2016


Facilitating the Behavioral Treatment of Cannabis Use Disorder


Condition:   Cannabis Dependence
Interventions:   Drug: CI-581a;   Drug: CI-581b;   Behavioral: Motivational Enhancement Therapy (MET);   Behavioral: Mindfulness Based Relapse Prevention
Sponsors:   New York State Psychiatric Institute;   National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified October 2016


Neural Indices Associated With Relapse in Cannabis Dependence


Condition:   Cannabis Dependence
Intervention:   Other: fMRI
Sponsors:   University of Electronic Science and Technology of China;   German Research Foundation;   University Hospital, Bonn
Recruiting - verified June 2016


Social and Emotional Brain Function in Cannabis Users


Condition:   Cannabis Dependence
Intervention:   Other: fMRI
Sponsors:   University of Electronic Science and Technology of China;   German Research Foundation;   University Hospital, Bonn
Completed - verified February 2017


Hormones and Reduction in Co-users of Marijuana and Nicotine


Condition:   Marijuana Dependence
Interventions:   Drug: Progesterone;   Drug: placebo
Sponsor:   University of Minnesota - Clinical and Translational Science Institute
Recruiting - verified May 2017


Pregnenolone and Marijuana Dependence


Condition:   Marijuana Dependence
Interventions:   Drug: Pregnenolone;   Other: Placebo
Sponsor:   Medical University of South Carolina
Completed - verified September 2016


Marijuana Treatment Project 4


Condition:   Marijuana Dependence
Interventions:   Behavioral: Contingency Management;   Behavioral: Individualized Assessment & Treatment;   Behavioral: Cognitive-Behavioral Treatment
Sponsor:   UConn Health
Active, not recruiting - verified March 2017


Integrated CBT for Cannabis Dependence With Co-occurring Anxiety Disorders


Conditions:   Cannabis Dependence;   Anxiety Disorders;   Cannabis Use Disorder;   Cannabis Abuse
Interventions:   Behavioral: Cognitive-Behavioral Therapy;   Behavioral: Motivation Enhancement Therapy;   Behavioral: Integrated Cannabis and Anxiety Reduction Treatment;   Behavioral: False Safety Behavior Elimination Therapy
Sponsors:   Louisiana State University and A&M College;   National Institute on Drug Abuse (NIDA)
Completed - verified August 2016


Effect of Oxytocin on Craving and Therapy Response


Condition:   Marijuana Dependence
Interventions:   Drug: Oxytocin;   Drug: Saline
Sponsor:   Medical University of South Carolina
Completed - verified November 2016


Quetiapine Pharmacotherapy for Cannabis Dependence


Condition:   Cannabis Dependence
Interventions:   Drug: Quetiapine;   Drug: Placebo
Sponsors:   New York State Psychiatric Institute;   National Institute on Drug Abuse (NIDA)
Active, not recruiting - verified May 2017


Achieving Cannabis Cessation-Evaluating N-Acetylcysteine Treatment


Condition:   Cannabis Dependence
Interventions:   Drug: N-Acetylcysteine;   Drug: Placebo
Sponsors:   Medical University of South Carolina;   National Institute on Drug Abuse (NIDA)
Completed - verified March 2017


Safety and Efficacy of a FAAH-Inhibitor to Treat Cannabis Withdrawal


Condition:   Cannabis Dependence
Interventions:   Drug: PF-04457845;   Drug: Placebo
Sponsors:   Yale University;   National Institute on Drug Abuse (NIDA)
Suspended - verified December 2016


Combination of Dronabinol and Clonidine for Cannabis Dependence in Patients With Schizophrenia


Conditions:   Cannabis Dependence;   Marijuana Dependence
Interventions:   Drug: Dronabinol;   Drug: Clonidine;   Drug: Placebo
Sponsors:   Mclean Hospital;   Brain & Behavior Research Foundation
Recruiting - verified April 2017


Vilazodone Treatment for Marijuana Dependence


Condition:   Marijuana Dependence
Interventions:   Drug: Vilazodone;   Drug: Placebo
Sponsors:   Medical University of South Carolina;   National Institute on Drug Abuse (NIDA)
Completed - verified July 2016


Open-Label Pilot Study of Guanfacine-Extended Release for the Treatment of Cannabis Dependence


Condition:   Cannabis Dependence
Intervention:   Drug: Guanfacine
Sponsor:   New York State Psychiatric Institute
Completed - verified March 2017


Treatment for Cannabis Withdrawal and Dependence


Condition:   Cannabis Dependence
Interventions:   Drug: Aprepitant;   Drug: Placebo;   Behavioral: Manual-guided behavioral counseling
Sponsors:   The Scripps Research Institute;   National Institute on Drug Abuse (NIDA)
Completed - verified March 2017


Nabilone for Cannabis Dependence: A Pilot Study


Conditions:   Cannabis Dependence;   Marijuana Dependence
Interventions:   Drug: Nabilone;   Drug: Placebo
Sponsors:   Mclean Hospital;   National Institute on Drug Abuse (NIDA)
Recruiting - verified September 2016


Gabapentin Treatment of Cannabis Dependence


Conditions:   Cannabis Dependence;   Cannabis Withdrawal;   Cognitive Deficits
Interventions:   Drug: gabapentin 1200mg/day;   Drug: Placebo;   Behavioral: Manual-guided behavioral counseling
Sponsors:   The Scripps Research Institute;   National Institute on Drug Abuse (NIDA)
Completed - verified December 2016


Buspirone Treatment for Marijuana Dependence


Condition:   Marijuana Dependence
Interventions:   Drug: Buspirone;   Drug: Placebo
Sponsors:   Medical University of South Carolina;   National Institute on Drug Abuse (NIDA)
Completed - verified July 2016


Clinical and Neurobiological Effects of Cannabis Dependence in Young Adults


Conditions:   Cannabis Dependence;   Cannabis Withdrawal
Interventions:   Drug: rimonabant;   Drug: placebo
Sponsors:   The Scripps Research Institute;   National Institute on Drug Abuse (NIDA)
Completed - verified April 2017


Ph1 Marinol Interaction Study - Part 2 - 1


Condition:   Marijuana Dependence
Interventions:   Drug: Placebo;   Drug: Dronabinol
Sponsor:   National Institute on Drug Abuse (NIDA)
Completed - verified August 2016


Ph1 Marinol Interaction Study - Part 1 - 1


Condition:   Marijuana Dependence
Intervention:   Drug: Dronabinol
Sponsor:   National Institute on Drug Abuse (NIDA)
Terminated - verified February 2007


Gabapentin Treatment of Cannabis Dependence


Condition:   Cannabis Dependence
Interventions:   Drug: Placebo;   Drug: Gabapentin
Sponsors:   The Scripps Research Institute;   National Institute on Drug Abuse (NIDA)
Completed - verified December 2016


Effect of Baclofen on Marijuana Withdrawal and Relapse


Condition:   Marijuana Dependence
Interventions:   Drug: Baclofen;   Drug: Marijuana;   Drug: Placebo
Sponsors:   New York State Psychiatric Institute;   National Institute on Drug Abuse (NIDA)
Completed - verified March 2017


Atomoxetine for the Treatment of Cannabis Dependence


Condition:   Cannabis Dependence
Intervention:   Drug: Atomoxetine
Sponsors:   National Institute on Drug Abuse (NIDA);   University of Pennsylvania
Completed - verified June 2010

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