Cannabis Addiction (Marijuana)



N-acetylcysteine for the Treatment of Cannabis Dependence: Working Mechanisms


Conditions:   Cannabis Use Disorder;   Cannabis Dependence
Interventions:   Drug: N-acetylcysteine;   Drug: Placebo Oral Tablet;   Other: Magnetic Resonance Imaging;   Other: Neurocognitive measures;   Other: Neuro-inflammatory measures
Sponsor:   Universitair Ziekenhuis Brussel
Recruiting


E-cigarette THC Study


Condition:   Marijuana Dependence
Intervention:   Drug: Tetrahydrocannabinol
Sponsors:   University of California, San Francisco;   National Institutes of Health (NIH)
Not yet recruiting


Facilitating the Behavioral Treatment of Cannabis Use Disorder


Condition:   Cannabis Dependence
Intervention:   Drug: CI-581a
Sponsors:   New York State Psychiatric Institute;   National Institute on Drug Abuse (NIDA)
Recruiting


Social and Emotional Brain Function in Cannabis Users


Condition:   Cannabis Dependence
Intervention:   Other: fMRI
Sponsors:   University of Electronic Science and Technology of China;   German Research Foundation;   University Hospital, Bonn
Completed


Study of Long-Acting Injectable Naltrexone to Treat Cannabis Dependence


Condition:   Cannabis Dependence
Intervention:   Drug: Long-acting injectable naltrexone
Sponsor:   New York State Psychiatric Institute
Completed


Marijuana Treatment Project 4


Condition:   Marijuana Dependence
Interventions:   Behavioral: Contingency Management;   Behavioral: Individualized Assessment & Treatment;   Behavioral: Cognitive-Behavioral Treatment
Sponsor:   UConn Health
Active, not recruiting


Baclofen Effects on Marijuana Dependence


Condition:   Marijuana Dependence
Interventions:   Drug: Baclofen;   Behavioral: Psychosocial;   Drug: Placebo
Sponsors:   University of Pennsylvania;   Pennsylvania Department of Health
Completed


Effect of Oxytocin on Craving and Therapy Response


Condition:   Marijuana Dependence
Interventions:   Drug: Oxytocin;   Drug: Saline
Sponsor:   Medical University of South Carolina
Completed


Sativex and Behavioral-relapse Prevention Strategy in Cannabis Dependence


Condition:   Cannabis Dependence
Interventions:   Behavioral: Motivational Enhancement/Cognitive Behavioral Therapy;   Drug: Sativex;   Drug: Placebo spray
Sponsors:   Centre for Addiction and Mental Health;   National Institute on Drug Abuse (NIDA)
Completed


Quetiapine Pharmacotherapy for Cannabis Dependence


Condition:   Cannabis Dependence
Interventions:   Drug: Quetiapine;   Drug: Placebo
Sponsors:   New York State Psychiatric Institute;   National Institute on Drug Abuse (NIDA)
Completed


Achieving Cannabis Cessation-Evaluating N-Acetylcysteine Treatment


Condition:   Cannabis Dependence
Interventions:   Drug: N-Acetylcysteine;   Drug: Placebo
Sponsors:   Medical University of South Carolina;   National Institute on Drug Abuse (NIDA)
Completed


Safety and Efficacy of a FAAH-Inhibitor to Treat Cannabis Withdrawal


Condition:   Cannabis Dependence
Interventions:   Drug: PF-04457845;   Drug: Placebo
Sponsors:   Yale University;   National Institute on Drug Abuse (NIDA)
Active, not recruiting


Treatment for Cannabis Withdrawal and Dependence


Condition:   Cannabis Dependence
Interventions:   Drug: Aprepitant;   Drug: Placebo;   Behavioral: Manual-guided behavioral counseling
Sponsors:   The Scripps Research Institute;   National Institute on Drug Abuse (NIDA)
Completed


Combination of Dronabinol and Clonidine for Cannabis Dependence in Patients With Schizophrenia


Conditions:   Cannabis Dependence;   Marijuana Dependence
Interventions:   Drug: Dronabinol;   Drug: Clonidine;   Drug: Placebo
Sponsors:   Mclean Hospital;   Brain & Behavior Research Foundation
Recruiting


Open-Label Pilot Study of Guanfacine-Extended Release for the Treatment of Cannabis Dependence


Condition:   Cannabis Dependence
Intervention:   Drug: Guanfacine
Sponsor:   New York State Psychiatric Institute
Completed


Gabapentin Treatment of Cannabis Dependence


Conditions:   Cannabis Dependence;   Cannabis Withdrawal;   Cognitive Deficits
Interventions:   Drug: gabapentin 1200mg/day;   Drug: Placebo;   Behavioral: Manual-guided behavioral counseling
Sponsors:   The Scripps Research Institute;   National Institute on Drug Abuse (NIDA)
Completed


Study of Quetiapine Treatment for Cannabis Dependence


Condition:   Cannabis Dependence
Intervention:   Drug: quetiapine
Sponsors:   New York State Psychiatric Institute;   National Institute on Drug Abuse (NIDA)
Completed


Clinical and Neurobiological Effects of Cannabis Dependence in Young Adults


Conditions:   Cannabis Dependence;   Cannabis Withdrawal
Interventions:   Drug: rimonabant;   Drug: placebo
Sponsors:   The Scripps Research Institute;   National Institute on Drug Abuse (NIDA)
Completed


An Open-Label Trial of N-Acetylcysteine in Cannabis Dependent Adolescents


Condition:   Cannabis Dependence
Intervention:   Drug: N-Acetylcysteine
Sponsors:   Medical University of South Carolina;   National Institute on Drug Abuse (NIDA);   American Academy of Child Adolescent Psychiatry.
Completed


Ph1 Marinol Interaction Study - Part 2 - 1


Condition:   Marijuana Dependence
Interventions:   Drug: Placebo;   Drug: Dronabinol
Sponsor:   National Institute on Drug Abuse (NIDA)
Completed


Ph1 Marinol Interaction Study - Part 1 - 1


Condition:   Marijuana Dependence
Intervention:   Drug: Dronabinol
Sponsor:   National Institute on Drug Abuse (NIDA)
Terminated


Gabapentin Treatment of Cannabis Dependence


Condition:   Cannabis Dependence
Interventions:   Drug: Placebo;   Drug: Gabapentin
Sponsors:   The Scripps Research Institute;   National Institute on Drug Abuse (NIDA)
Completed


Effect of Baclofen on Marijuana Withdrawal and Relapse


Condition:   Marijuana Dependence
Interventions:   Drug: Baclofen;   Drug: Marijuana;   Drug: Placebo
Sponsors:   New York State Psychiatric Institute;   National Institute on Drug Abuse (NIDA)
Completed


Atomoxetine for the Treatment of Cannabis Dependence


Condition:   Cannabis Dependence
Intervention:   Drug: Atomoxetine
Sponsors:   National Institute on Drug Abuse (NIDA);   University of Pennsylvania
Completed


Marijuana Treatment Project - 3


Condition:   Marijuana Dependence
Interventions:   Behavioral: Reinforcement for homework completion;   Behavioral: Reinforcement for Abstinence;   Behavioral: Case Management
Sponsors:   UConn Health;   National Institute on Drug Abuse (NIDA)
Completed

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